{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:54:37Z","timestamp":1784548477066,"version":"3.55.0"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,5,2]],"date-time":"2012-05-02T00:00:00Z","timestamp":1335916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background\/Purpose<\/jats:title><jats:p>Narrowband ultraviolet <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">NB\u2010UVB<\/jats:styled-content>) has been accepted as an effective therapy for generalized vitiligo. On the other hand, different factors seem to contribute to a good response. The purpose of this study is to evaluate the influence of disease duration on its clinical response to <jats:styled-content style=\"fixed-case\">NB\u2010UVB<\/jats:styled-content> phototherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this open and uncontrolled study, vitiligo was considered \u2018recent\u2019 when the duration of disease was less than or equal to 4 years and \u2018long standing\u2019 when it was greater than 4 years. The patients received <jats:styled-content style=\"fixed-case\">NB\u2010UVB<\/jats:styled-content> thrice weekly with an initial dose of 200\u2009m<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>\/cm<jats:sup>2<\/jats:sup> and 10% increments at each subsequent treatment. After categorizing the clinical response to four groups (mild, moderate, good, and excellent), duration of disease and clinical response to <jats:styled-content style=\"fixed-case\">NB\u2010UVB<\/jats:styled-content> were correlated statistically using the <jats:italic>t<\/jats:italic>\u2010test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 63 patients: 34 women and 29 men, aged 6\u201360 years. The mean of disease duration was 10.13\u2009\u00b1\u20099.1 years. Vitiligo was \u2018recent\u2019 in 26 and \u2018long standing\u2019 in 37 patients. The mean of overall response was 51.94\u2009\u00b1\u200918.48%. Higher grades of response were more prevalent in patients with recent vitiligo than those with long\u2010standing disease, and there was also statistically significant difference in overall response between these two groups of disease duration (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u2009=\u20090.023).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The early treatment of generalized vitiligo may enhance the chance of successful repigmentation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0781.2012.00648.x","type":"journal-article","created":{"date-parts":[[2012,5,2]],"date-time":"2012-05-02T05:49:12Z","timestamp":1335937752000},"page":"115-119","source":"Crossref","is-referenced-by-count":42,"title":["Evaluation of the effect of disease duration in generalized vitiligo on its clinical response to narrowband ultraviolet <scp>B<\/scp> phototherapy"],"prefix":"10.1111","volume":"28","author":[{"given":"Zahra","family":"Hallaji","sequence":"first","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Ghiasi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayat","family":"Eisazadeh","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maede","family":"Rayati Damavandi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Razi Hospital, Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02278.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1997.03890480045006"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.09.004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1586\/edm.10.34"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/978-3-540-69361-1_42","volume-title":"Vitiligo","author":"Leone G","year":"2010"},{"key":"e_1_2_6_7_1","first-page":"2053","volume-title":"Dermatology","author":"Honigsmann H","year":"2008"},{"key":"e_1_2_6_8_1","first-page":"913","volume-title":"Dermatology","author":"Ortone JP","year":"2008"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.5.578"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90133-6"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2001.114752"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2005.01837.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02329.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2006.00222.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03233.x"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0781.2012.00648.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0781.2012.00648.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T12:28:05Z","timestamp":1697286485000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0781.2012.00648.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,2]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1600-0781.2012.00648.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0781.2012.00648.x","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,2]]}}}