{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:33:39Z","timestamp":1761964419045},"reference-count":5,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,9,12]],"date-time":"2012-09-12T00:00:00Z","timestamp":1347408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Photoderm Photoimm Photomed"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>From <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch to <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ugust 2010, there was a shortage of encapsulated liquid 8\u2010methoxypsoralen (8\u2010<jats:styled-content style=\"fixed-case\">MOP<\/jats:styled-content>), the psoralen used for bath psoralen plus UVA (<jats:styled-content style=\"fixed-case\">PUVA<\/jats:styled-content>) in <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>oronto, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>anada. Patients were forced to discontinue bath <jats:styled-content style=\"fixed-case\">PUVA<\/jats:styled-content> treatment and were transitioned to other therapeutic modalities, including narrowband <jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> (nb<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>). A retrospective chart review was conducted of all patients who discontinued bath <jats:styled-content style=\"fixed-case\">PUVA<\/jats:styled-content> due to the unavailability of 8\u2010<jats:styled-content style=\"fixed-case\">MOP<\/jats:styled-content>, with a focus on those who were switched to nb<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>. Sixty\u2010three patients discontinued <jats:styled-content style=\"fixed-case\">PUVA<\/jats:styled-content>, 39 of whom were switched to nb<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>. Fifteen of 17 patients with mycosis fungoides (<jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>) who were switched to nb<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> improved, and patients with earlier\u2010stage disease were more likely to improve. Ten of 13 (77%) psoriasis patients improved with nb<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content>, including two patients whose psoriasis cleared completely. All three small\u2010plaque parapsoriasis patients who switched to nb<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> had complete clearance of their lesions. In conclusion, nb<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> may be a suitable alternative for patients with <jats:styled-content style=\"fixed-case\">MF<\/jats:styled-content>, small\u2010plaque parapsoriasis and psoriasis who cannot access <jats:styled-content style=\"fixed-case\">PUVA<\/jats:styled-content> therapy.<\/jats:p>","DOI":"10.1111\/j.1600-0781.2012.00683.x","type":"journal-article","created":{"date-parts":[[2012,9,13]],"date-time":"2012-09-13T01:38:34Z","timestamp":1347500314000},"page":"267-268","source":"Crossref","is-referenced-by-count":9,"title":["Narrowband <scp>UVB<\/scp> as an effective substitute for psoralen plus <scp>UVA<\/scp>: lessons from a psoralen shortage"],"prefix":"10.1111","volume":"28","author":[{"given":"Aaron M.","family":"Drucker","sequence":"first","affiliation":[{"name":"Division of Dermatology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akerke","family":"Baibergenova","sequence":"additional","affiliation":[{"name":"Division of Dermatology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl F.","family":"Rosen","sequence":"additional","affiliation":[{"name":"Division of Dermatology University of Toronto  Toronto Canada"},{"name":"Division of Dermatology University Health Network  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil H.","family":"Shear","sequence":"additional","affiliation":[{"name":"Division of Dermatology University of Toronto  Toronto Canada"},{"name":"Division of Dermatology Women's College Hospital and Sunnybrook Health Science Centre  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,9,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta4400"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03500.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2005.01752.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70008-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2010.00525.x"}],"container-title":["Photodermatology, Photoimmunology &amp; Photomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0781.2012.00683.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0781.2012.00683.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T11:11:24Z","timestamp":1700565084000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0781.2012.00683.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,12]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1111\/j.1600-0781.2012.00683.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0781.2012.00683.x","archive":["Portico"],"relation":{},"ISSN":["0905-4383","1600-0781"],"issn-type":[{"value":"0905-4383","type":"print"},{"value":"1600-0781","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,12]]}}}