{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T07:48:14Z","timestamp":1764402494606},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,4,21]],"date-time":"2011-04-21T00:00:00Z","timestamp":1303344000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:p><jats:bold>Background: <\/jats:bold> The effects of exposure to hyperbaric oxygen on ultraviolet B (UVB) irradiation\u2010induced melanin pigmentations of skins and on senile spot sizes of faces were investigated.<\/jats:p><jats:p><jats:bold>Methods: <\/jats:bold> In the first experiment, male subjects were irradiated with UVB on their upper arms for inducing erythema and the subsequent melanin pigmentation. They were exposed to a hyperbaric environment at 1.25 atmospheres absolute (ATA) with 32% oxygen for 1\u2003h\/day, three times per week. In the second experiment, female subjects were exposed to a hyperbaric environment at 1.25\u2003ATA with 32% oxygen for 1\u2003h\/day, two times per week.<\/jats:p><jats:p><jats:bold>Results: <\/jats:bold> In the first experiment, melanin pigmentations lightened after 4 weeks of exposure to hyperbaric oxygen. In the second experiment, senile spot sizes became small after 12 weeks of exposure to hyperbaric oxygen.<\/jats:p><jats:p><jats:bold>Conclusion: <\/jats:bold> We concluded that exposure to hyperbaric oxygen used in this study accelerates both the fading in melanin pigmentation and the decrease in senile spot size.<\/jats:p>","DOI":"10.1111\/j.1600-0846.2011.00502.x","type":"journal-article","created":{"date-parts":[[2011,4,21]],"date-time":"2011-04-21T09:01:37Z","timestamp":1303376497000},"page":"332-338","source":"Crossref","is-referenced-by-count":9,"title":["Hyperbaric oxygen improves ultraviolet B irradiation\u2010induced melanin pigmentation and diminishes senile spot 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