{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:05:50Z","timestamp":1787015150597,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,1,4]],"date-time":"2012-01-04T00:00:00Z","timestamp":1325635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2013,2]]},"abstract":"\n Background<\/jats:title>\n \n As the inflammatory scalp conditions share similar clinical manifestations of scaling, inflammation, and pruritus, the differential diagnosis of these lesions; especially between scalp psoriasis (\n SP<\/jats:styled-content>\n ) and seborrheic dermatitis (\n SD<\/jats:styled-content>\n ) is sometimes difficult.\n <\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n \n The aim of this study was to investigate the differences on the hair surface in\n SP<\/jats:styled-content>\n and\n SD<\/jats:styled-content>\n for a clinical diagnosis, using atomic force microscopy (\n AFM<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n The hair shafts of 14 patients and 28 patients with\n SP<\/jats:styled-content>\n and\n SD<\/jats:styled-content>\n respectively, were taken from the lesional region. Hairs from healthy adults not having any hair diseases were also examined in the same way for the controls. Surface characteristics of\n SP<\/jats:styled-content>\n and\n SD<\/jats:styled-content>\n \u2010affected hair shafts such as, pitting, scale thickness, and roughness, were observed on the\n AFM<\/jats:styled-content>\n images.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n One hundred percentage and four percentage of the patients with\n SP<\/jats:styled-content>\n and\n SD<\/jats:styled-content>\n respectively had macropits on their hair shafts. In both the\n SP<\/jats:styled-content>\n and\n SD<\/jats:styled-content>\n \u2010affected hairs, the scale thickness was more than 4\u2010fold than that in the control hairs. The surface of\n SP<\/jats:styled-content>\n \u2010affected hairs was rougher than that of\n SD<\/jats:styled-content>\n \u2010affected and control hairs.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The differences in hair shafts between\n SP<\/jats:styled-content>\n and\n SD<\/jats:styled-content>\n were investigated noninvasively using\n AFM<\/jats:styled-content>\n . The presence of macropits could be helpful in the differentiation between\n SP<\/jats:styled-content>\n and\n SD<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/j.1600-0846.2011.00608.x","type":"journal-article","created":{"date-parts":[[2012,1,4]],"date-time":"2012-01-04T20:52:57Z","timestamp":1325710377000},"source":"Crossref","is-referenced-by-count":14,"title":["A comparative study of hair shafts in scalp psoriasis and seborrheic dermatitis using atomic force microscopy"],"prefix":"10.1111","volume":"19","author":[{"given":"Kyung Sook","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering School of Medicine Kyung Hee University Seoul Korea"},{"name":"Healthcare Industry Research Institute Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. K.","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. J.","family":"Ahn","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. R.","family":"Haw","sequence":"additional","affiliation":[{"name":"Department of Dermatology School of Medicine Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hun\u2010Kuk","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering School of Medicine Kyung Hee University Seoul Korea"},{"name":"Healthcare Industry Research Institute Kyung Hee University Seoul Korea"},{"name":"Program of Medical Engineering Kyung Hee University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,4]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"912","article-title":"Scalp psoriasis: an overview of the disease and available therapies","volume":"9","author":"Crowley J.","year":"2010","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_6_3_1","first-page":"191","volume-title":"Handbook of diseases of the hair and scalp","author":"Sinclair R","year":"1999"},{"key":"e_1_2_6_4_1","volume-title":"The nail in health and disease","author":"Zaias N","year":"1990"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.02740.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.56.930"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(97)78153-0"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03372.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200102030-00005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31816421fd"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.04.058"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb02696.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0074-7696(05)43001-6"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06108.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1998.00456.x"},{"key":"e_1_2_6_16_1","first-page":"601","article-title":"Basal\u2010cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia","volume":"140","author":"Smedts F","year":"1992","journal-title":"Am J Pathol"}],"container-title":["Skin Research and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0846.2011.00608.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0846.2011.00608.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T08:56:36Z","timestamp":1697273796000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0846.2011.00608.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1,4]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["10.1111\/j.1600-0846.2011.00608.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0846.2011.00608.x","archive":["Portico"],"relation":{},"ISSN":["0909-752X","1600-0846"],"issn-type":[{"value":"0909-752X","type":"print"},{"value":"1600-0846","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1,4]]}}}