{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:03:25Z","timestamp":1757541805948},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T00:00:00Z","timestamp":1368057600000},"content-version":"vor","delay-in-days":8863,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[1989,2]]},"abstract":"<jats:p><jats:bold>ABSTRACT: <\/jats:bold> Rats mated after laminin immunization had higher frequencies of resorptions (57%) than those immunized with bovine serum albumin (20%) and had sera that were toxic to cultured rat embryos. In addition, sera from rats immunized with laminin A chains but not B chains were toxic to cultured embryos. The toxicity of sera to embryos was related to the reactivity of sera to specific laminin fragments rather than to sera IgG levels against intact laminin. In addition, resorptions in pregnant rats immunized with laminin were not related to the sera antilaminin IgG levels. However, levels of uterine antilaminin IgA, the predominant uterine isotype, increased considerably during the first 3.5 days of pregnancy, while sera antilaminin IgG remained constant.<\/jats:p>","DOI":"10.1111\/j.1600-0897.1989.tb00549.x","type":"journal-article","created":{"date-parts":[[2013,5,9]],"date-time":"2013-05-09T12:13:03Z","timestamp":1368101583000},"page":"57-64","source":"Crossref","is-referenced-by-count":7,"title":["In Vitro and In Vivo Embryo Toxicity of Antilaminin Antibodies in the Rat"],"prefix":"10.1111","volume":"19","author":[{"given":"BENJAMIN S.","family":"WEEKS","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NORMAN W.","family":"KLEIN","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,9]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198507183130304"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108413"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1986.106"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1402000210"},{"key":"e_1_2_1_6_2","first-page":"346","article-title":"Abortion in mice induced by intraveneous injections of antibodies to type IV collagen or laminin","volume":"110","author":"Foidart JM","year":"1983","journal-title":"Am J Pathol."},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/jez.1402160116"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/tera.1420400107"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7053560"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0378(84)90027-5"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod25.5.997"},{"key":"e_1_2_1_12_2","article-title":"Autoantibodies to laminin and other basement membrane proteins in sera from monkeys with histories of reproductive failure identified by cultures of whole rat embryos","author":"Carey SW","year":"1989","journal-title":"Fertil Steril."},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0120509"},{"key":"e_1_2_1_14_2","first-page":"347","article-title":"Analysis of sera from monkeys with histories of fetal wastage and the identification of teratogenicity in sera from human chronic spontaneous aborters using rat embryo cultures","volume":"1","author":"Carey SW","year":"1983","journal-title":"Troph Res."},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1984.tb04177.x"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)83607-4"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.142.3600.1677"},{"key":"e_1_2_1_18_2","first-page":"359","volume-title":"Manual of Clinical Immunology","author":"Voller A","year":"1980"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(84)90185-6"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.9.4350"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150050212"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1210\/endo-106-3-1020"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)52451-6"},{"key":"e_1_2_1_24_2","first-page":"171","volume-title":"Introductory Laboratory Animal Science","author":"Arrington LR","year":"1978"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(87)90109-7"},{"key":"e_1_2_1_26_2","first-page":"173","volume-title":"Basic and Clinical Immunology","author":"Stites DP","year":"1982"},{"key":"e_1_2_1_27_2","doi-asserted-by":"crossref","first-page":"511","DOI":"10.4049\/jimmunol.136.2.511","article-title":"Experimental autoimmune encephalomyelitis mediated by T lymphocyte lines: Genotype of antigen\u2010presenting cells influences immunodominant epitope of basic protein","volume":"136","author":"Beraud E","year":"1986","journal-title":"J Immunol."},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(80)90379-6"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.7.2183"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod32.1.90"},{"key":"e_1_2_1_31_2","first-page":"645","article-title":"Immunologic aspects of recurrent abortion and fetal death","volume":"70","author":"Scott JR","year":"1987","journal-title":"Obstet Gynecol."},{"key":"e_1_2_1_32_2","first-page":"113","article-title":"Congenital heart block in newborns of mothers with connective tissue disease. Circulation. 1977; 56:82\u201390. 32. Lauwerys R, Bernard A, Roels H, Bucket JP, Gennart JP, Mahieu P, Foidart JM. Anti\u2010laminin antibodies in workers exposed to mercury vapour","volume":"17","author":"McCue CM","year":"1983","journal-title":"Toxicol Lett."}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0897.1989.tb00549.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0897.1989.tb00549.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T12:49:48Z","timestamp":1697978988000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0897.1989.tb00549.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,2]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1989,2]]}},"alternative-id":["10.1111\/j.1600-0897.1989.tb00549.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0897.1989.tb00549.x","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,2]]}}}