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Immunohistochemitry and reverse transcriptase polymerase chain reaction techniques were used to identify IL\u201017 receptor protein and mRNA, respectively. The effects of IL\u201017 on JEG\u20103 cell proliferation and invasion were tested using the BrdU incorporation and the Matrigel invasion assays, respectively.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> IL\u201017 increased the invasive capacity of JEG\u20103 cells but had no effect on the proliferation and multinucleated formation of JEG\u20103 cells.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> In this JEG\u20103 cell model of human trophoblast, the IL\u201017R and IL\u201017 may have a regulatory role in trophoblast invasion.<\/jats:p>","DOI":"10.1111\/j.1600-0897.2006.00366.x","type":"journal-article","created":{"date-parts":[[2006,3,8]],"date-time":"2006-03-08T14:42:05Z","timestamp":1141828925000},"page":"291-300","source":"Crossref","is-referenced-by-count":41,"title":["The Effect of Interleukin\u201017 on the Proliferation and Invasion of JEG\u20103 Human Choriocarcinoma 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