{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T18:14:01Z","timestamp":1771006441706,"version":"3.50.1"},"reference-count":59,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,6,11]],"date-time":"2007-06-11T00:00:00Z","timestamp":1181520000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:sec><jats:title>Problem<\/jats:title><jats:p>The aim of the study was to investigate and compare the concentrations of interleukin (IL)\u20102, IL\u20106, and IL\u201010 in serum of women with mild pre\u2010eclampsia, severe pre\u2010eclampsia, eclampsia, and normotensive pregnancy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method of study<\/jats:title><jats:p>A total of 69 consecutive cases, 38 mild pre\u2010eclampsia, 20 severe pre\u2010eclampsia, 11 eclampsia, and 20 normotensive controls were included in this study. Serum IL\u20102, IL\u20106, and IL\u201010 levels were determined using enzyme\u2010linked immunosorbent assay method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Gestational age (<jats:italic>P\u2003<\/jats:italic>=\u20030.210) and body mass index (<jats:italic>P\u2003<\/jats:italic>=\u20030.214) between the groups were similar. The mean concentration of serum IL\u20102 and IL\u20106 were not different between the groups (<jats:italic>P<\/jats:italic>\u2003=\u20030.261, <jats:italic>P<\/jats:italic>\u2003=\u20030.141 respectively). The median concentrations of serum IL\u201010 in patients with mild and severe pre\u2010eclampsia were similar (<jats:italic>P\u2003<\/jats:italic>&lt;\u20030.282) and was significantly lower than those of controls (<jats:italic>P\u2003<\/jats:italic>&lt;\u20030.001) and patients with eclampsia (<jats:italic>P\u2003<\/jats:italic>&lt;\u20030.001). In patients with eclampsia, the median concentration of IL\u201010 was significantly higher than that of all other groups (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.001 for each comparison).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pre\u2010eclampsia is associated with a deficiency serum IL\u201010. High serum IL\u201010 is correlated with the presence of eclampsia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/j.1600-0897.2007.00491.x","type":"journal-article","created":{"date-parts":[[2007,6,11]],"date-time":"2007-06-11T17:10:42Z","timestamp":1181581842000},"page":"56-64","source":"Crossref","is-referenced-by-count":45,"title":["Maternal Serum Interleukin\u201010, Interleukin\u20102 and Interleukin\u20106 in Pre\u2010Eclampsia and Eclampsia"],"prefix":"10.1111","volume":"58","author":[{"given":"Bunyamin","family":"Borekci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hulya","family":"Aksoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ragip Atakan","family":"Al","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berna","family":"Demircan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sedat","family":"Kadanali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,6,11]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2002.0930"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2005.10.007"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/1071-5576(95)00007-2"},{"key":"e_1_2_7_5_2","first-page":"937","article-title":"Increased concentrations of cytokines interleukin\u20106 and interleukin\u20101 receptor antagonist in plasma of women with preeclampsia: a mechanism for endothelial dysfunction?","volume":"84","author":"Greer IA","year":"1994","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000052943"},{"key":"e_1_2_7_7_2","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.4049\/jimmunol.163.6.3491","article-title":"A deficiency of placental IL\u201010 in preeclampsia","volume":"163","author":"Hennessy A","year":"1999","journal-title":"J\u00a0Immunol"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(02)02077-X"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2005.05.003"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2005.00278.x"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2004.00161.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(99)00065-2"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.1998.770602.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1043-4666(03)00220-5"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.8755-8920.2000.440405.x"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70325-X"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(98)00300-7"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.86.6.2505"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0412.2003.00206.x"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.1998.tb00398.x"},{"key":"e_1_2_7_21_2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5144\/0256-4947.2000.4","article-title":"Interleukins in preeclampsia","volume":"20","author":"Olusi SO","year":"2000","journal-title":"Ann Saudi Med"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/35094583"},{"key":"e_1_2_7_23_2","first-page":"761","volume-title":"Hypertensive Disorders in Pregnancy. Williams Obstetrics","author":"Cunningham FG","year":"2005"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2001.0781"},{"key":"e_1_2_7_25_2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0020-7292(96)90112-5","article-title":"Hypertension in pregnancy. Number 219\u2013January 1996 (replaces no. 91, February 1986). Committee on Technical Bulletins of the American College of Obstetricians and Gynecologists","volume":"53","author":"ACOG technical bulletin","year":"1996","journal-title":"Int J Gynaecol Obstet"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1067\/S0002-9378(03)00651-3"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.09.015"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70496-0"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.217.2.r00nv44371"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.05.069"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(97)00048-3"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R200003200"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1997.14.451"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(99)00148-4"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000027211.73567.FA"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.1997.4621483.x"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.1999.640437.x"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-001-8170-y"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000057976.53301.69"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000155622.68580.DC"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.10.2325"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01280.x"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2005.00298.x"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-1211(00)00140-6"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-1211(98)00024-2"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1053\/seiz.2001.0575"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2004.04.007"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(00)00234-4"},{"key":"e_1_2_7_49_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1995.tb01013.x"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1528-1157.2002.02002.x"},{"key":"e_1_2_7_51_2","doi-asserted-by":"publisher","DOI":"10.1159\/000097189"},{"key":"e_1_2_7_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1991.tb16974.x"},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(01)00345-9"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1043"},{"key":"e_1_2_7_55_2","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.102.014977"},{"key":"e_1_2_7_56_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106178"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08778-0"},{"key":"e_1_2_7_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2004.10.011"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17987-2"},{"key":"e_1_2_7_60_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2004.00071.x"}],"container-title":["American Journal of Reproductive Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-0897.2007.00491.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-0897.2007.00491.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T12:08:02Z","timestamp":1697026082000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-0897.2007.00491.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6,11]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1111\/j.1600-0897.2007.00491.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-0897.2007.00491.x","archive":["Portico"],"relation":{},"ISSN":["1046-7408","1600-0897"],"issn-type":[{"value":"1046-7408","type":"print"},{"value":"1600-0897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6,11]]}}}