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As in other tissues, antigen handling and processing in the decidualized endometrium constitutes a primary event in the onset of immune responses and is therefore likely to determine their stimulatory or tolerogenic nature. Maternal antigen\u2010presenting cells [macrophages and dendritic cells (DCs)] are scattered throughout the decidualized endometrium during all stages of pregnancy and appear to be important players in this feto\u2010maternal immune adjustment. This review focuses on the characterization of decidual macrophages and DCs, as well as their involvement in cell\u2013cell interactions within the decidual leukocyte network, which are likely to influence uterine and placental homeostasis as well as the local maternal immune responses to the fetus during pregnancy.<\/jats:p>","DOI":"10.1111\/j.1600-0897.2007.00511.x","type":"journal-article","created":{"date-parts":[[2007,8,7]],"date-time":"2007-08-07T01:17:34Z","timestamp":1186449454000},"page":"255-267","source":"Crossref","is-referenced-by-count":105,"title":["Antigen\u2010Presenting Cells and Materno\u2010Fetal Tolerance: An Emerging Role for Dendritic 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