{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:17:33Z","timestamp":1782775053320,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2010,2,3]],"date-time":"2010-02-03T00:00:00Z","timestamp":1265155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Rep Immunol"],"published-print":{"date-parts":[[2010,5]]},"abstract":"<jats:p> <jats:bold>Citation<\/jats:bold> Sarapik A, Haller\u2010Kikkatalo K, Utt M, Teesalu K, Salumets A, Uibo R. Serum anti\u2010endometrial antibodies in infertile women \u2013 potential risk factor for implantation failure. Am J Reprod Immunol 2010<\/jats:p><jats:p><jats:bold>Problem\u2002<\/jats:bold> Female infertility patients with diverse etiologies show increased production of autoantibodies.<\/jats:p><jats:p><jats:bold>Method of study\u2002<\/jats:bold> Immunoblot analysis of sera from patients with endometriosis and tubal factor infertility (TFI) and mass spectrometry identification of candidate antigens.<\/jats:p><jats:p><jats:bold>Results\u2002<\/jats:bold> The immunoblot results demonstrated the presence of IgA and IgG anti\u2010endometrial antibodies (AEA) to various antigens at molecular weights ranging from 10 to 200\u2003kDa. Differences were detected in certain AEA reactions between the patients\u2019 groups and particular AEA were associated with <jats:italic>in vitro<\/jats:italic> fertilization (IVF) implantation failure. IgA AEA to a 47\u2010kDa protein were more prevalent in TFI patients and were associated with unsuccessful IVF treatment. This antigen was subsequently identified as \u03b1\u2010enolase.<\/jats:p><jats:p><jats:bold>Conclusion\u2002<\/jats:bold> Determination of the presence and spectra of AEA in patients with endometriosis and TFI undergoing IVF may be a useful marker to predict their pregnancy outcome.<\/jats:p>","DOI":"10.1111\/j.1600-0897.2010.00808.x","type":"journal-article","created":{"date-parts":[[2010,2,4]],"date-time":"2010-02-04T02:41:23Z","timestamp":1265251283000},"page":"349-357","source":"Crossref","is-referenced-by-count":32,"title":["ORIGINAL ARTICLE: Serum Anti\u2010endometrial Antibodies in Infertile Women \u2013 Potential Risk Factor for Implantation 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