{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:03:53Z","timestamp":1787015033529,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,5,13]],"date-time":"2004-05-13T00:00:00Z","timestamp":1084406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dental Traumatology"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:p>\n                    <jats:bold>Abstract<\/jats:bold>\n                    \u2002\u2013\u2002This\n                    <jats:italic>in\u2003vitro<\/jats:italic>\n                    study aimed to assess dentin permeability quantitatively after the use of different irrigants into the pulp chamber, with or without ultrasonic activation, before the application of an internal bleaching agent. Thirty maxillary anterior teeth, treated endodontically, were randomly assigned to six groups, according to the irrigant used: group I, distilled water; group II, 17% EDTA; group III, 1% sodium hypochlorite; for groups IV, V, and VI, respectively, the same solutions were used, but were ultrasonicated. In groups I, II, and III, the irrigant that filled the pulp chamber was left undisturbed for 15\u2003s and was then aspirated; in groups IV, V, and IV, the irrigants were placed into the pulp chamber, ultrasonic\u2010activated for 15\u2003s, and were then aspirated. This sequence was repeated three times for all groups. Afterwards, for all groups, the pulp chamber was dried, filled with a bleaching agent, and sealed with glass ionomer cement. At each change of the whitening agent, these procedures were repeated. Then, the temporary restorations were removed, access cavities were cleaned, and teeth were immersed in a 10% copper sulfate aqueous solution, submitted to vacuum and immersed in a 1% rubianic acid alcohol solution. Copper ion penetration was revealed by the rubianic acid. After staining, roots were removed at the cemento\u2010enamel junction (CEJ) and sectioned in a mesiodistal direction starting from the cervical plug level. The sections were thinned, observed under an optical microscope, the images were digitized, and copper ion penetration was measured in each section using a specific software. Means and SD were: group I, 2.41 (\u00b11.45); group II, 5.22 (\u00b11.79); group III, 8.32 (\u00b12.55); group IV, 3.73 (\u00b10.89); group V, 14.83 (\u00b14.99); and group VI, 10.51 (\u00b12.65). Statistical analysis using two\u2010way\n                    <jats:sc>anova<\/jats:sc>\n                    and Tukey test showed that, regardless of the irrigant, ultrasonication increased dentinal permeability (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.01). Comparing the overall effectiveness of the tested solutions, EDTA yielded the greatest increase in dentinal permeability (\n                    <jats:italic>P<\/jats:italic>\n                    \u2003&lt;\u20030.01). Based on these results, it may be concluded that use of ultrasonic\u2010activated irrigants in the pulp chamber, before the accomplishment of internal dental bleaching procedures, may result in a remarkable increase of dentin permeability, which may enhance the efficiency of the whitening agent.\n                  <\/jats:p>","DOI":"10.1111\/j.1600-4469.2004.00231.x","type":"journal-article","created":{"date-parts":[[2004,5,13]],"date-time":"2004-05-13T08:54:30Z","timestamp":1084438470000},"page":"164-168","source":"Crossref","is-referenced-by-count":13,"title":["<i>In\u2003vitro<\/i>\n                    assessment of dentinal permeability after the use of ultrasonic\u2010activated irrigants in the pulp chamber before internal dental bleaching"],"prefix":"10.1111","volume":"20","author":[{"given":"Laise Daniela","family":"Carrasco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesus Djalma","family":"P\u00e9cora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izabel Cristina","family":"Fr\u00f6ner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,5,13]]},"reference":[{"key":"e_1_2_5_2_2","volume-title":"Complete dental bleaching.","author":"Goldstein RE","year":"1995"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1985.tb00561.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(86)80258-8"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)81181-7"},{"key":"e_1_2_5_6_2","first-page":"129","article-title":"In vitro action of various bleaching agents on the microhardness of human dentin","volume":"5","author":"P\u00e9cora JD","year":"1994","journal-title":"Braz Dent J"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(89)80129-3"},{"key":"e_1_2_5_8_2","first-page":"13","article-title":"Bleaching of root filled teeth","volume":"19","author":"Marin P","year":"1993","journal-title":"Aust Endod Newsletter"},{"key":"e_1_2_5_9_2","first-page":"105","article-title":"Five\u2010year follow\u2010up of internal bleaching","volume":"10","author":"Glockner K","year":"1999","journal-title":"Braz Dent J"},{"key":"e_1_2_5_10_2","first-page":"37","article-title":"Estudo in vitro da permeabilidade dentin\u00e1ria ap\u00f3s aplica\u00e7\u00e3o de agentes clareadores","volume":"14","author":"Saquy PC","year":"1992","journal-title":"Rev Paul Odontol"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)80956-8"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(88)80004-9"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(81)90243-2"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(83)90001-8"},{"key":"e_1_2_5_15_2","first-page":"12","article-title":"The use of ultrasonic in root canal therapy and root resection","volume":"12","author":"Richiman MJ","year":"1957","journal-title":"J Dent Med"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(76)90035-9"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(83)80119-8"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.1989.tb00501.x"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(99)80220-9"},{"key":"e_1_2_5_20_2","first-page":"2","article-title":"Avalia\u00e7\u00e3o comparativa da permeabilidade dentin\u00e1ria radicular entre o preparo do canal efetuado manualmente e com aux\u00edlio de ultra som","volume":"5","author":"Feller C","year":"1986","journal-title":"Rev Paul Odont"},{"key":"e_1_2_5_21_2","first-page":"157","article-title":"Avalia\u00e7\u00e3o da per meabilidade dentin\u00e1ria radicular ap\u00f3s a instrumenta\u00e7\u00e3o manual e ultra\u2010s\u00f4nica,utilizando um m\u00e9todo histoqu\u00edmico","volume":"44","author":"Gariba Silva R","year":"1990","journal-title":"Rev Assoc Paul Cirurg Dent"},{"key":"e_1_2_5_22_2","first-page":"37","article-title":"Effects of various irrigating solutions on the cleaning of the root canal with ultrasonic instrumentation","volume":"1","author":"Vansan LP","year":"1990","journal-title":"Braz Dent J"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)81610-9"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.1995.tb03121.x"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2001.00395.x"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2002.00488.x"},{"key":"e_1_2_5_27_2","first-page":"493","article-title":"Clareamento de dentes: t\u00e9cnica alternativa usando aparelho de ultrasom","volume":"34","author":"Lacerda AG","year":"1986","journal-title":"RGO"},{"key":"e_1_2_5_28_2","first-page":"49","article-title":"Altera\u00e7\u00e3o da permeabilidade dentin\u00e1ria frente a v\u00e1rios agentes branqueadores estudo in vitro","volume":"39","author":"Mantesso A","year":"1996","journal-title":"STOMA"},{"key":"e_1_2_5_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)81632-8"},{"key":"e_1_2_5_30_2","first-page":"34","article-title":"Apresenta\u00e7\u00e3o de um m\u00e9todo qu\u00edmico que revela in vitro a passagem do per\u00f3xido de hidrog\u00eanio a 30% atrav\u00e9s da dentina radicular","volume":"13","author":"P\u00e9cora JD","year":"1991","journal-title":"Rev Paul Odont"},{"key":"e_1_2_5_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1996.tb00102.x"},{"key":"e_1_2_5_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1991.tb00204.x"},{"key":"e_1_2_5_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(07)80199-3"},{"key":"e_1_2_5_34_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1997.0426"},{"key":"e_1_2_5_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(88)80090-6"}],"container-title":["Dental Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-4469.2004.00231.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-4469.2004.00231.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T02:16:55Z","timestamp":1697163415000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-4469.2004.00231.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5,13]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1111\/j.1600-4469.2004.00231.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-4469.2004.00231.x","archive":["Portico"],"relation":{},"ISSN":["1600-4469","1600-9657"],"issn-type":[{"value":"1600-4469","type":"print"},{"value":"1600-9657","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,5,13]]}}}