{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T08:28:17Z","timestamp":1774686497068,"version":"3.50.1"},"reference-count":47,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T00:00:00Z","timestamp":1093996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2004,9,1]],"date-time":"2004-09-01T00:00:00Z","timestamp":1093996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"vor","delay-in-days":6671,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2004,9]]},"DOI":"10.1111\/j.1600-6143.2004.00525.x","type":"journal-article","created":{"date-parts":[[2004,8,12]],"date-time":"2004-08-12T06:48:03Z","timestamp":1092293283000},"page":"1466-1474","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"title":["High Pretransplant Serum Levels of CXCL10\/IP-10 Are Related to Increased Risk of Renal Allograft Failure"],"prefix":"10.1016","volume":"4","author":[{"given":"Mario","family":"Rotondi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Rosati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Buonamano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Lasagni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Lazzeri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Pradella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vittorio","family":"Fossombroni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Calogero","family":"Cirami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Liotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"La Villa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Serio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Bertoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Salvadori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Romagnani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1111\/j.1600-6143.2004.00525.x_bib1","series-title":"Principles and Practice in Renal Transplantation","first-page":"41","article-title":"Immunobiology of allograft rejection","author":"SM","year":"2000"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib2","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev.immunol.18.1.217","article-title":"The biology of chemokines and their receptors","author":"Rossi","year":"2000","journal-title":"Annu Rev Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib3","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1084\/jem.187.1.129","article-title":"Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s","volume":"187","author":"Bonecchi","year":"1998","journal-title":"J Exp Med"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib4","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1084\/jem.184.3.963","article-title":"Chemokine receptor specific for IP10 and Mig: structure, function, and expression in activated T-lymphocytes","volume":"184","author":"Loetscher","year":"1996","journal-title":"J Exp Med"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib5","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1084\/jem.194.9.1375","article-title":"Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regu- lates monocyte recruitment","volume":"194","author":"Janatpour","year":"2001","journal-title":"J Exp Med"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib6","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.4049\/jimmunol.167.4.1862","article-title":"Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells","volume":"167","author":"Penna","year":"2001","journal-title":"J Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib7","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1182\/blood.V97.3.601","volume":"97","author":"Romagnani","year":"2001","journal-title":"Blood"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib8","doi-asserted-by":"crossref","first-page":"24286","DOI":"10.1074\/jbc.271.39.24286","article-title":"Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response","volume":"271","author":"Wang","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib9","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1681\/ASN.V10122518","article-title":"Role for interactions between IP-10\/Mig and their receptor (CXCR3) in proliferative glomerulonephritis","volume":"10","author":"Romagnani","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib10","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1681\/ASN.V13153","article-title":"IP-10 and Mig production by glomerular cells in human proliferative glomerulonephritis and regulation by nitric oxide","volume":"13","author":"Romagnani","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib11","doi-asserted-by":"crossref","first-page":"9945","DOI":"10.1074\/jbc.M010303200","article-title":"Signal transduction by the chemokine receptor CXCR3: activation of Ras\/ERK Src, and phosphatidylinositol 3-kinase\/Akt controls cell migration and proliferation in human vascular pericytes","volume":"276","author":"Bonacchi","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib12","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1172\/JCI9775","article-title":"Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity","volume":"107","author":"Romagnani","year":"2001","journal-title":"J Clin Invest"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib13","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.it.2004.02.006","article-title":"Romagnani S. CXC chemokines the regulatory link between inflammation and angiogenesis","volume":"81","author":"Romagnani","year":"2004","journal-title":"Trends Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib14","article-title":"CXCR3-binding chemokines: multifaceted therapeutic targets","author":"Lazzeri","year":"2004","journal-title":"Curr Drug Targets Immune Endocr Metabol Disord"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib15","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1084\/jem.193.8.975","article-title":"Donor-derived IP-10 initiates development of acute allograft rejection","volume":"193","author":"Hancock","year":"2001","journal-title":"J Exp Med"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib16","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1084\/jem.192.10.1515","article-title":"Requirement of the chemokine receptor CXCR3 for acute allograft rejection","volume":"192","author":"Hancock","year":"2000","journal-title":"J Exp Med"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib17","doi-asserted-by":"crossref","first-page":"3205","DOI":"10.4049\/jimmunol.168.7.3205","article-title":"Donor TCell Activation Initiates Small Bowel Allograft Rejection Through an IFN-\u03b3-Inducible Protein-10-Dependent Mechanism","volume":"168","author":"Zhang","year":"2002","journal-title":"J Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib18","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1053\/ajkd.2001.22076","article-title":"Expression of chemokines and chemokine receptors during human renal transplant rejection","volume":"37","author":"Segerer","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib19","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1016\/S0002-9440(10)64126-0","article-title":"CXCR3 and its ligand CXCL10 are expressed by inflammatory cells infiltrating lung allografts and mediate chemotaxis of T cells at sites of rejection","volume":"158","author":"Agostini","year":"2001","journal-title":"Am J Pathol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib20","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1161\/hc4601.098010","article-title":"Expression of the chemokine receptor CXCR3 and its ligand IP-10 during human cardiac allograft rejection","volume":"104","author":"Melter","year":"2001","journal-title":"Circulation"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib21","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1097\/00007890-200301150-00013","article-title":"Chemokine and chemokine receptor gene expression indicates acute rejection of human cardiac transplants","volume":"75","author":"Fahmy","year":"2003","journal-title":"Transplantation"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib22","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.4049\/jimmunol.169.3.1556","volume":"169","author":"Zhao","year":"2002","journal-title":"J Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib23","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1034\/j.1600-6143.2003.00151.x","article-title":"Glomerular Infiltration by CXCR3+ ICOS+ Activated T Cells in Chronic Allograft Nephropathy with Transplant Glomerulopathy","volume":"3","author":"Akalin","year":"2003","journal-title":"Am J Transplant"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib24","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0002-9440(10)64171-5","article-title":"Expression of IP-10\/CXCL10 and MIG\/CXCL9 in the thyroid and increased levels of IP-10\/CXCL10 in the serum of patients with recent-onset Graves' disease","volume":"161","author":"Romagnani","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib25","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1182\/blood.V92.8.2668","article-title":"Divergent effects of interleukin-4 and interferon-gamma on macrophage-derived chemokine production: an amplification circuit of polarized T helper 2 responses","volume":"92","author":"Bonecchi","year":"1998","journal-title":"Blood"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib26","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/1521-4141(200001)30:1<204::AID-IMMU204>3.0.CO;2-G","article-title":"Macrophage-derived chemokine production by activated human T cells in vitro and in vivo: preferential association with the production of type 2 cytokines","volume":"30","author":"Galli","year":"2000","journal-title":"Eur J Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib27","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF03345149","article-title":"Role for interferon-gamma inducible chemokines in endocrine autoimmunity: an expanding field","volume":"26","author":"Rotondi","year":"2003","journal-title":"J Endocrinol Invest"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib28","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0952-7915(03)00103-1","article-title":"Chemokines and their receptors as markers of allograft rejection and targets for immunosuppression","volume":"15","author":"Hancock","year":"2003","journal-title":"Curr Opin Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib29","first-page":"441","article-title":"Report of the Third Banff Conference on Allograft Pathology (July 20\u201324, 1995) on classification and lesion scoring in renal allograft pathology","volume":"28","author":"Solez","year":"1996","journal-title":"Transplant Proc"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib30","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/S0952-7915(02)00386-2","article-title":"Late deterioration of organ transplants. a problem in injury and homeostasis","volume":"14","author":"Gourishankar","year":"2002","journal-title":"Curr Opin Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib31","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1097\/01.ASN.0000014256.75920.5B","article-title":"for the Collaborative Transplant Study. Identification of highly responsive kidney transplant recipients using pretransplant soluble CD30","volume":"13","author":"S\u00fcsal","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib32","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1096\/fj.02-0908fje","article-title":"HayGlass KT. Allergic humans are hyporesponsive to a CXCR3-ligand-mediated Th1 immunity-promoting loop","volume":"18","author":"Campbell","year":"2004","journal-title":"Faseb J"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib33","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.4049\/jimmunol.168.7.3195","article-title":"IFN-gamma-inducible protein 10 (IP-10; CXCL10) -deficient mice reveal a role for IP-10 in effector T cell generation and trafficking","volume":"168","author":"Dufour","year":"2002","journal-title":"J Immunol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib34","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1084\/jem.20021897","article-title":"An alternatively spliced variant of CXCR3 mediates the IP-10, Mig and I-TAC induced-inhibition of endothelial cell growth and acts as functional receptor for PF-4","volume":"197","author":"Lasagni","year":"2003","journal-title":"J Exp Med"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib35","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1038\/ki.1994.117","article-title":"Plasma levels of IL-1beta, TNF-alpha and their specific inhibitors in undialyzed chronic renal failure, CAPD and hemodialysis patients","volume":"45","author":"Pereira","year":"1994","journal-title":"Kidney Int"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib36","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/S0272-6386(03)00353-6","article-title":"Associations between circulating inflammatory markers and residual renal function in CRF patients","volume":"41","author":"Pecoits-Filho","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib37","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1681\/ASN.V1271549","article-title":"The microinflammatory state in uremia: causes and potential consequences","volume":"12","author":"Kaysen","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib38","doi-asserted-by":"crossref","first-page":"S206","DOI":"10.1046\/j.1523-1755.2001.59780206.x","article-title":"Molecular aspects of T- and B-cell function in uremia","volume":"78","author":"Girndt","year":"2001","journal-title":"Kidney Int Suppl"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib39","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1093\/ndt\/15.8.1217","article-title":"T-cell activation follows Th1 rather than Th2 pattern in haemodialysis patients","volume":"15","author":"Sester","year":"2000","journal-title":"Nephrol Dial Transplant"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib40","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1097\/00007890-200003150-00034","article-title":"Pretransplant systemic inflammation and acute rejection after renal transplantation","volume":"69","author":"Perez","year":"2000","journal-title":"Transplantation"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib41","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1053\/ajkd.2002.32794","article-title":"Pretransplant serum C-reactive protein and the risk of chronic allograft nephropathy in renal transplant recipients: a pilot case-control study","volume":"39","author":"Fink","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib42","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0041-1345(01)02815-9","article-title":"High-sensitivity C-reactive protein as pretransplant marker for acute rejection and cardiovascular morbidity","volume":"34","author":"Lauzurica","year":"2002","journal-title":"Transplant Proc"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib43","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1053\/j.ajkd.2003.11.011","article-title":"Pretransplantation levels of C-reactive protein predict all-cause and cardiovascular mortality, but not graft outcome, in kidney transplant recipients","volume":"43","author":"Varagunam","year":"2004","journal-title":"Am J Kidney Dis"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib44","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.1600-6143.2004.00354.x","article-title":"Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction","volume":"4","author":"Hu","year":"2004","journal-title":"Am J Transplant"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib45","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1161\/01.CIR.0000069270.16498.75","article-title":"Elevated serum levels of the CXCR3 chemokine ITAC are associated with the development of transplant coronary artery disease","volume":"107","author":"Kao","year":"2003","journal-title":"Circulation"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib46","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0009-9120(02)00276-X","article-title":"Circulating monocyte chemoattractant protein-1 in heart transplant recipients with cardiac allograft vasculopathy","volume":"35","author":"Beaudeux","year":"2002","journal-title":"Clin Biochem"},{"key":"10.1111\/j.1600-6143.2004.00525.x_bib47","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1034\/j.1600-6143.2003.00132.x","article-title":"Enzyme linked immunosorbent spot (ELISPOT) assay for interferon-gamma independently predicts renal function in kidney transplant recipients","volume":"3","author":"Hricik","year":"2003","journal-title":"Am J Transplant"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-6143.2004.00525.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522079540?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522079540?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/j.1600-6143.2004.00525.x\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:31:07Z","timestamp":1761625867000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522079540"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9]]},"references-count":47,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2004,9]]}},"alternative-id":["S1600613522079540"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-6143.2004.00525.x","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2004,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High Pretransplant Serum Levels of CXCL10\/IP-10 Are Related to Increased Risk of Renal Allograft Failure","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/j.1600-6143.2004.00525.x","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}