{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:30:30Z","timestamp":1760887830194},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,1,11]],"date-time":"2006-01-11T00:00:00Z","timestamp":1136937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dental Traumatology"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:p><jats:bold>Abstract\u2002\u2013\u2002<\/jats:bold> The treatment of choice for tooth avulsion is replantation. The ideal replantation should be realized as quickly as possible, or at least, the avulsed tooth should be kept in an adequate solution to preserve the periodontal ligament attached to the root. If that is not possible, treatment of the radicular surface should be done in order to prevent radicular resorption. The purpose of this study was to test sodium alendronate as a substance for topical treatment of the radicular surface of avulsed teeth in an attempt to prevent the occurrence of dental resorptions. Fifty\u2010four rat maxillary right central incisors were extracted and replanted. Group I \u2013 extra\u2010alveolar dry period of 15\u2003min, intracanal dressing with calcium hydroxide (CALEN<jats:sup>\u00ae<\/jats:sup>, S.S. White, Artigos Dent\u00e1rios LTDA, Rio de Janeiro, Brazil) and replantation; Groups II and III \u2013 extra\u2010alveolar dry periods of 30 and 60\u2003min, respectively, immersion in 1% sodium hypochlorite for 30\u2003min for removal of the periodontal ligament, washing in saline solution for 5\u2003min, and treatment of the radicular surface with 3.2\u2003mg\/l sodium alendronate solution for 10\u2003min. Intracanal dressing with calcium hydroxide and replantation followed. At 15, 60, and 90\u2003days post\u2010reimplantation, the animals were killed and the samples obtained and processed for microscopic analysis. The results indicated that sodium alendronate was able to reduce the incidence of radicular resorption, but not of dental ankylosis. No significant differences were observed regarding variations in the extra\u2010alveolar periods among the groups.<\/jats:p>","DOI":"10.1111\/j.1600-9657.2006.00417.x","type":"journal-article","created":{"date-parts":[[2006,1,11]],"date-time":"2006-01-11T14:40:07Z","timestamp":1136990407000},"page":"30-35","source":"Crossref","is-referenced-by-count":40,"title":["Evaluation of the topical effect of alendronate on the root surface of extracted and replanted teeth. Microscopic analysis on rats\u2019 teeth"],"prefix":"10.1111","volume":"22","author":[{"given":"Adriana","family":"Lustosa\u2010Pereira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto Brand\u00e3o","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivaldo Gomes","family":"De Moraes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norberti","family":"Bernardineli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clovis Monteiro","family":"Bramante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Antunes","family":"Bortoluzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,11]]},"reference":[{"key":"e_1_2_5_2_2","volume-title":"Textbook and color atlas of traumatic injuries to the teeth","author":"Andreasen JO","year":"1994"},{"key":"e_1_2_5_3_2","first-page":"329","article-title":"Etiology and pathogenesis of traumatic dental injuries. 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