{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:46:33Z","timestamp":1770749193734,"version":"3.50.0"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2009,3,6]],"date-time":"2009-03-06T00:00:00Z","timestamp":1236297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dental Traumatology"],"published-print":{"date-parts":[[2009,4]]},"abstract":"<jats:p><jats:bold>Abstract\u2002\u2013\u2002<\/jats:bold><jats:bold> Background:\u2002<\/jats:bold> Current clinical guidelines recommend prescribing systemic antibiotic therapy (SAT) for patients having an avulsed permanent tooth replanted. The principles of evidence\u2010based dentistry can be used to assess whether this is the best approach based on currently\u2010available evidence. The objective of this study was to use the principles of evidence\u2010based dentistry to answer the PICO question: (P) for a replanted avulsed permanent tooth, (I) is prescribing SAT, (C) compared with not prescribing SAT, (O) associated with an increased likelihood of successful periodontal healing after tooth replantation?<\/jats:p><jats:p><jats:bold>Materials and methods:\u2002<\/jats:bold> A literature search was performed across four internet databases (Ovid Medline, Cochrane Library, PubMed, ISI Web of Science), for relevant citations (<jats:italic>n<\/jats:italic>\u2003=\u200335\u2003702). Limiting citations to those in English and removing duplicates produced a set of titles (<jats:italic>n<\/jats:italic>\u2003=\u200314\u2003742) that were sieved according to evidence\u2010based dentistry principles. Relevant titles were selected for abstract assessment (<jats:italic>n<\/jats:italic>\u2003=\u2003782), identifying papers for examination (<jats:italic>n<\/jats:italic>\u2003=\u200374). Inclusion criteria were applied and three papers (326 total teeth) met the final criteria for meta\u2010analysis.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Meta\u2010analyses found no statistically significant difference between prescribing or not prescribing antibiotics for acceptable periodontal healing without progressive root resorption (common odds ratio\u2003=\u20030.90, SE\u2003=\u20030.29, 95% confidence intervals\u2003=\u20030.51\u20131.58).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The evidence for an association between prescribing SAT and an increased likelihood of acceptable periodontal healing outcome is inconclusive. This investigation of antibiotic use as defined in the clinical guidelines indicates there is inconclusive clinical evidence from studies of replanted avulsed human teeth to either contradict or support the guideline. Pending future research to the contrary, dentists are recommended to follow current guidelines in prescribing SAT when replanting avulsed teeth.<\/jats:p>","DOI":"10.1111\/j.1600-9657.2008.00736.x","type":"journal-article","created":{"date-parts":[[2009,3,6]],"date-time":"2009-03-06T07:45:38Z","timestamp":1236325538000},"page":"158-164","source":"Crossref","is-referenced-by-count":49,"title":["An evidence\u2010based assessment of the clinical guidelines for replanted avulsed teeth. Part II: prescription of systemic antibiotics"],"prefix":"10.1111","volume":"25","author":[{"given":"Susan Elisabeth","family":"Hinckfuss","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise Brearley","family":"Messer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,3,6]]},"reference":[{"key":"e_1_2_8_2_2","first-page":"448","article-title":"Clinical practice guidelines in dentistry: part II by dentists, for dentists","volume":"67","author":"Sutherland SE","year":"2001","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-263X.1998.00066.x"},{"key":"e_1_2_8_4_2","first-page":"176","article-title":"Postreplanation management of avulsed teeth: an endodontic literature review","volume":"48","author":"Pavek DI","year":"2000","journal-title":"Gen Dent"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-9657.2001.170501.x"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2007.00605.x"},{"key":"e_1_2_8_7_2","first-page":"120","article-title":"Clinical guideline on management of acute dental trauma","volume":"27","author":"American Academy of Pediatric Dentistry","year":"2005","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_8_2","volume-title":"Recommended Guidelines of the American Association of Endodontists for the treatment of traumatic dental injuries","author":"American Association of Endodontists","year":"2004"},{"key":"e_1_2_8_9_2","first-page":"357","article-title":"Management of avulsed permanent incisors: a decision analysis based on changing concepts","volume":"23","author":"Lee JY","year":"2001","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_10_2","first-page":"383","volume-title":"Textbook and color atlas of traumatic injuries to the teeth","author":"Andreasen JO","year":"1994"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1986.tb00124.x"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1997.tb00032.x"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1998.tb00842.x"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1989.tb00354.x"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.1990.tb03028.x"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1995.tb00462.x"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1995.tb00464.x"},{"key":"e_1_2_8_18_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016356609028222"},{"key":"e_1_2_8_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1991.tb00436.x"},{"issue":"3","key":"e_1_2_8_20_2","first-page":"CD004152","article-title":"Antibiotics to prevent complications following dental implant treatment","author":"Esposito M","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1600-4469.2001.00001.x"},{"key":"e_1_2_8_22_2","first-page":"251","article-title":"Therapeutic protocols for avulsed permanent teeth: review and clinical update","volume":"26","author":"Ram D","year":"2004","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1998.tb00825.x"},{"key":"e_1_2_8_24_2","first-page":"147","article-title":"Discoloration of permanent front teeth in 3,157 Norwegian children due to tetracyclines and other factors","volume":"86","author":"Ulvestad H","year":"1978","journal-title":"Scand J Dent Res"},{"key":"e_1_2_8_25_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1990.tb00413.x"},{"key":"e_1_2_8_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2005.00330.x"},{"key":"e_1_2_8_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2008.00727.x"},{"key":"e_1_2_8_28_2","unstructured":"Ovid Medline Library. Available at:http:\/\/portal.isiknowledge.com.ezproxy.lib.unimelb.edu.au\/portal.cgi\/portal.cgi?DestApp=MEDLINE(last accessed December 2007)."},{"key":"e_1_2_8_29_2","unstructured":"Cochrane Library. Available at:http:\/\/www3.interscience.wiley.com\/cgi\u2010bin\/mrwhome\/106568753\/HOME(last accessed December 2007)."},{"key":"e_1_2_8_30_2","unstructured":"PubMed. Available at:http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez(last accessed December 2007)."},{"key":"e_1_2_8_31_2","unstructured":"ISI Web of Science. Available at:http:\/\/isiwebofknowledge.com\/(last accessed December 2007)."},{"key":"e_1_2_8_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1995.tb00461.x"},{"key":"e_1_2_8_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1995.tb00463.x"},{"key":"e_1_2_8_34_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1990.tb00385.x"},{"key":"e_1_2_8_35_2","volume-title":"Version 4.2 for Windows","author":"Review Manager (RevMan) [Computer program]","year":"2002"},{"key":"e_1_2_8_36_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7300.1479"},{"key":"e_1_2_8_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_8_38_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-9657.2003.00197.x"}],"container-title":["Dental Traumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1600-9657.2008.00736.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1600-9657.2008.00736.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T07:12:26Z","timestamp":1697008346000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1600-9657.2008.00736.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,6]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["10.1111\/j.1600-9657.2008.00736.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1600-9657.2008.00736.x","archive":["Portico"],"relation":{},"ISSN":["1600-4469","1600-9657"],"issn-type":[{"value":"1600-4469","type":"print"},{"value":"1600-9657","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3,6]]}}}