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The purpose of this study was to evaluate the effect of Emdogain<jats:sup>\u00ae<\/jats:sup> and 24% ethylenediamine tetraacetic acid (EDTA) root conditioning on periodontal healing of replanted dog\u2019s teeth. Teeth were extracted, endodontically treated and preconditioned as follows: group 1, Emdogain<jats:sup>\u00ae<\/jats:sup>; group 2, Emdogain<jats:sup>\u00ae<\/jats:sup>\u2003+\u2003EDTA and group 3, EDTA. Teeth were replanted after 30\u2003min extraoral time, splinted for 15\u2003days and animals sacrificed after 8\u2003weeks of observation. Histological evaluation was performed using hematoxylin\/eosin and Masson trichrome and results scored based on previously reported criteria for histological evaluation. Replacement root resorption was histologically diagnosed in all groups except in the negative control. A parametric analysis showed no statistically significant differences between experimental groups. Root preconditioning with Emdogain<jats:sup>\u00ae<\/jats:sup> alone or in combination with 24% EDTA showed no evidence of regeneration of collagen fibers and consequently did not prevent the development of replacement root resorption on replanted dog\u2019s teeth.<\/jats:p>","DOI":"10.1111\/j.1600-9657.2008.00741.x","type":"journal-article","created":{"date-parts":[[2009,1,21]],"date-time":"2009-01-21T06:49:13Z","timestamp":1232520553000},"page":"43-50","source":"Crossref","is-referenced-by-count":15,"title":["The effect of Emdogain<sup>\u00ae<\/sup> and 24% EDTA root conditioning on periodontal healing of replanted dog\u2019s teeth"],"prefix":"10.1111","volume":"25","author":[{"given":"Nayelli","family":"Guzm\u00e1n\u2010Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flores 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