{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:45:56Z","timestamp":1762505156852},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T00:00:00Z","timestamp":1152230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:p><jats:bold>Background:\u2002<\/jats:bold> Limited published scientific evidence is available to provide guidance to clinicians on possible increased risks of invasive oral procedures associated with the human immunodeficiency virus (HIV) status of the patient. The aim of this study was to assess post\u2010procedural complications in patients infected with HIV.<\/jats:p><jats:p><jats:bold>Material and methods:\u2002<\/jats:bold> This was a retrospective cross\u2010sectional study of the records of 101 consecutive HIV patients treated at the School of Dentistry of Madrid Complutense University and Sandoval STD Clinic in Madrid between January 2003 and February 2005. Data were gathered by an experienced dental practitioner using a structured epidemiological questionnaire for information on gender, age, HIV transmission category, medical history, hepatitis B virus (HBV) or hepatitis C virus (HCV) coinfection and other diseases, TCD4+ and TCD8+ count, HIV viral load (VL), platelet count, neutrophil count, international normalized ratio and haemoglobin level; tobacco and alcohol intake, highly active antiretroviral treatment and presence of oral lesions. Information was also collected on complications related to dental treatment (invasive or non\u2010invasive) during the previous 6\u2003months. Chi\u2010squared test and Fisher's exact test were used to establish statistical significance.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Data were gathered on 314 dental procedures in 101 patients. The overall complication rate was 2.2% (7\/314); in 147 invasive procedures, seven complications (4.8%) were documented (one persistent pain, two prolonged bleeding, three infections, one bone sequestrum) including extractions, periodontal scaling, endodontic treatment and biopsy. No differences were found in TCD4+, TCD8+, platelet count, HBV or HCV co\u2010infections or HIV VL between patients with and\/or without complications. Patients with complications were mainly in B stage of HIV disease (<jats:italic>P<\/jats:italic>\u2003=\u20030.020). Oral lesions and smoking habit &gt;20\u2003cig\u2003day<jats:sup>\u22121<\/jats:sup> were documented in 83.3% (<jats:italic>P<\/jats:italic>\u2003=\u20030.086) and 50% (<jats:italic>P<\/jats:italic>\u2003=\u20030.060), respectively, of patients with complications.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> The complication rate was 2.2% overall and 4.8% after invasive dental procedures. Presence of oral lesions, smoking habit or HIV clinical stage B may be predictive factors for oral complications in HIV patients. No relationship was found between complications and virological, immunological or other laboratory values. Studies with wider samples and negative control group are warranted to confirm the absence of an association between HIV positivity and higher risk of oral complications.<\/jats:p>","DOI":"10.1111\/j.1601-0825.2006.01262.x","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T23:14:08Z","timestamp":1152314048000},"page":"110-116","source":"Crossref","is-referenced-by-count":24,"title":["Oral complication risks after invasive and non\u2010invasive dental procedures in HIV\u2010positive patients"],"prefix":"10.1111","volume":"13","author":[{"given":"J","family":"Campo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Cano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Del Romero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Hernando","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Bascones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,1,22]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Principles of Oral Health Management for the HIV\/AIDS Patient","author":"Abel SN","year":"2000"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.1989.tb01186.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(93)90401-O"},{"key":"e_1_2_6_5_1","first-page":"515","article-title":"Dental management of patients with human immunodeficiency virus","volume":"34","author":"Campo\u2010Trapero J","year":"2003","journal-title":"Quintessence Int"},{"issue":"17","key":"e_1_2_6_6_1","first-page":"1","article-title":"1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults","volume":"41","author":"CDC","year":"1992","journal-title":"MMWR"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.0022-0337.1989.53.3.tb02303.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-7125(05)70526-5"},{"key":"e_1_2_6_9_1","article-title":"Treatment planning and Ongoing Care. 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