{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T19:57:28Z","timestamp":1780084648002,"version":"3.54.0"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,1,25]],"date-time":"2007-01-25T00:00:00Z","timestamp":1169683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> The objective of the present study was to compare a new type of symptomatic lichenoid reaction, specifically located on the mucosal side of the lips, and associated with microorganisms, with a matched group presenting with reticular oral lichen planus (OLP) of the buccal mucosa.<\/jats:p><jats:p><jats:bold>Patients and methods:\u2002<\/jats:bold> The mean age for both groups was 66\u2003years with a predominance of women (62%). The lichenoid reaction group (<jats:italic>n<\/jats:italic>\u2003=\u200325) presented with a reticular reaction pattern embracing various degrees of erythema. Patients presenting with OLP had similar lesions confined to the buccal mucosa but not on the mucosal side of the lips.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> In both groups, 80% were on any type of medication. However, 56% of the patients with lichenoid reactions medicated with more than three drugs compared with 29% (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05) in the OLP group. The former group more often used medicaments prescribed for cardiovascular diseases (48%<jats:italic>vs<\/jats:italic> 25%). Twenty\u2010two of the patients with lichenoid reactions were treated with chlorhexidine. In 80% of these patients (<jats:italic>n<\/jats:italic>\u2003=\u200318), the lesions improved or completely healed, indicating a microbial association.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Lichenoid reactions present on the mucosal side of the lips may be initiated by microbial plaque precipitated on the buccal surfaces of the anterior teeth.<\/jats:p>","DOI":"10.1111\/j.1601-0825.2006.01312.x","type":"journal-article","created":{"date-parts":[[2007,1,25]],"date-time":"2007-01-25T11:44:47Z","timestamp":1169725487000},"page":"402-406","source":"Crossref","is-referenced-by-count":40,"title":["Microbial\u2010associated oral lichenoid reactions"],"prefix":"10.1111","volume":"13","author":[{"given":"K","family":"B\u00e4ckman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Jontell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,5,23]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"67","article-title":"Microflora in oral ecosystems in subjects with hyposalivation due to medicines or of unknown origin","volume":"3","author":"Almstahl A","year":"2005","journal-title":"Oral Health Prev Dent"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(94)90065-5"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1996.tb00268.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1998.tb01978.x"},{"key":"e_1_2_5_6_1","first-page":"185","article-title":"A ten\u2010year cross\u2010sectional and follow\u2010up study of salivary flow rates and mutans streptococci and lactobacillus counts in elderly Swedish individuals","volume":"1","author":"Fure S","year":"2003","journal-title":"Oral Health Prev Dent"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3083.2001.00988.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(90)90241-J"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.01.009"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016358809004748"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.06.077"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2000.290603.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1995.tb01966.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.1996.tb00076.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(05)80217-3"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2006.00419.x"},{"key":"e_1_2_5_17_1","first-page":"251","article-title":"Hepatitis C virus and oral lichen planus\/lichenoid reactions: lack of evidence for an association","volume":"46","author":"Roy KM","year":"2000","journal-title":"Clin Lab"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)80444-2"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb00112.x"}],"container-title":["Oral Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1601-0825.2006.01312.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1601-0825.2006.01312.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T16:19:52Z","timestamp":1697041192000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1601-0825.2006.01312.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,23]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["10.1111\/j.1601-0825.2006.01312.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1601-0825.2006.01312.x","archive":["Portico"],"relation":{},"ISSN":["1354-523X","1601-0825"],"issn-type":[{"value":"1354-523X","type":"print"},{"value":"1601-0825","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,23]]}}}