{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:49:35Z","timestamp":1772160575342,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:\u2002<\/jats:bold>\n                    To present a clinical report of palatal zygomycosis, its epidemiological, mycological features, and our treatment experience.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design:\u2002<\/jats:bold>\n                    Retrospective report.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Subjects and methods:\u2002<\/jats:bold>\n                    This is a 25\u2010year long retrospective trial of clinically and mycologically proven cases of zygomycosis. Some patients underwent a biopsy of the palatal lesion and autopsy. This study reports the treatment experience with amphotericin\u2003B alone and in combination with itraconazole and fluconazole.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:\u2002<\/jats:bold>\n                    Twenty\u2010one cases (18.75%) of zygomycosis with palatal involvement were included in the study, from a total of 112 cases screened. Mean age was 36.5\u2003years, with 18 adults and three children. The associated pre\u2010disposing factors were: ketoacidotic diabetes (five type\u20101 and 15 type\u20102), and acute leukaemia in one patient. The clinical varieties were as follows: 19 cases of rhinocerebral (RC) involvement and two disseminated cases. Palatal ulcers occurred in 3\/21 early cases (14.3%) and in 16\/21 cases after the nasal involvement. All patients received amphotericin\u2003B; in four patients, it was combined with itraconazole and four with fluconazole. Clinical and mycological cure was achieved in 4\/21 patients (19.04%).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusion:\u2002<\/jats:bold>\n                    Zygomycosis with palatal involvement occurs in around 18% of cases, usually associated with RC modalities; it has an acute and generally lethal course.\n                  <\/jats:p>","DOI":"10.1111\/j.1601-0825.2007.01433.x","type":"journal-article","created":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T23:28:18Z","timestamp":1201908498000},"page":"569-574","source":"Crossref","is-referenced-by-count":35,"title":["Palatal zygomycosis: experience of 21 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