{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T20:54:36Z","timestamp":1771016076944,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2009,7,8]],"date-time":"2009-07-08T00:00:00Z","timestamp":1247011200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:p><jats:bold>Objective:\u2002<\/jats:bold> To investigate the incidence and risk factors of post\u2010tooth extraction sepsis in patients without locoregional infection.<\/jats:p><jats:p><jats:bold>Subjects and Methods:\u2002<\/jats:bold> We assessed all claim records of the Taiwanese National Health Insurance program in 2005. Admissions for patients aged \u226516\u2003years containing a discharge diagnosis of sepsis, and who received tooth extraction within 14\u2003days before the admission were identified. Patient charts were reviewed to confirm the diagnosis of sepsis and rule out other infection sources. The relationship between postextraction sepsis (PES) and clinical parameters was analyzed.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Thirty\u2010three of the 2\u2003223\u2003971 extraction cases met the criteria of PES, an incidence of 1.48 per 100\u2003000, and seven patients (21.2%) died of the disease. Aging significantly increased the risk of PES (<jats:italic>P\u2003<\/jats:italic>&lt;<jats:italic>\u2003<\/jats:italic>0.001). Pre\u2010existing comorbidities were found in 20 of the 33 cases, with diabetes mellitus and hematologic diseases the most common. The method, number, and position of extraction had no influence on PES incidence. Blood cultures were positive in 25 patients (75.8%) and isolates included species of the <jats:italic>Streptococcus, Actinomyces<\/jats:italic>, <jats:italic>Klebsiella, Bacteroides, Prevotella,<\/jats:italic> and <jats:italic>Enterococcus<\/jats:italic> genera.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Tooth extraction is associated with a low but significant risk of postoperative sepsis, especially in the elderly and patients with underlying diseases.<\/jats:p>","DOI":"10.1111\/j.1601-0825.2009.01596.x","type":"journal-article","created":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T23:20:46Z","timestamp":1247181646000},"page":"602-607","source":"Crossref","is-referenced-by-count":17,"title":["Post\u2010tooth extraction sepsis without locoregional infection \u2013 a population\u2010based study in Taiwan"],"prefix":"10.1111","volume":"15","author":[{"given":"J\u2010J","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u2010J","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u2010P","family":"Kao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u2010H","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u2010J","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u2010L","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u2010H","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u2010H","family":"Jeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u2010H","family":"Kok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,10,7]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199206000-00025"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1128\/jcm.26.10.2105-2109.1988","article-title":"Oral infections and septicemia in immunocompromised patients with hematologic malignancies","volume":"26","author":"Bergmann OJ","year":"1998","journal-title":"J Clin Microbiol"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V87.5.1710.1710"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00003796"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197804)41:4<1610::AID-CNCR2820410452>3.0.CO;2-B"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.8.3.244"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345900690101201"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9136(199701)14:1<29::AID-DIA300>3.0.CO;2-V"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000117317.18092.E4"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/427876"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(82)90483-2"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(02)80017-7"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.28.10.2205-2209.1990"},{"key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2337\/diab.39.3.271","article-title":"Effects of hyperglycemia on C3 and Candida albicans. 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