{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T05:29:27Z","timestamp":1789104567641,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,2,24]],"date-time":"2012-02-24T00:00:00Z","timestamp":1330041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p><jats:italic>Oral Diseases<\/jats:italic> (2012) <jats:bold>18,<\/jats:bold> 548\u2013557<\/jats:p><jats:p><jats:bold>Objective:\u2002<\/jats:bold> Keratocystic odontogenic tumors (KOTs) can be treated with Carnoy\u2019s solution, although this treatment modality is not free from complications. It is important to verify the incidence of complications after the use of Carnoy\u2019s solution and compare these with the literature.<\/jats:p><jats:p><jats:bold>Materials and methods:\u2002<\/jats:bold> This study verified the effects of a complementary treatment for KOTs and assessed the incidence of such complications as recurrence, infection, sequestrum formation, mandibular fracture, dehiscence, and neuropathy.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Twenty\u2010two KOTs treated with Carnoy\u2019s solution combined with peripheral ostectomy were included, and the follow\u2010up period varied from 12 to 78\u2003months with a mean of 42.9\u2003months. Complications included recurrence (4.5%), dehiscence (22.7%), infection (4.5%), and paresthesia (18.2%). No difference was found among lesions associated (9.1%) or not (0%) with nevoid basal cell carcinoma syndrome (<jats:italic>P<\/jats:italic>\u2003&gt;\u20030.05). Dehiscence was influenced by marsupialization (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.05), and paresthesia was observed exclusively in cases of mandibular canal fenestration (<jats:italic>P<\/jats:italic>\u2003&lt;\u20030.01).<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Complementary treatment with Carnoy\u2019s solution and peripheral ostectomy appear to provide efficient treatment for KOTs. Complications originating from the use of the solution are less frequent and less serious than complications associated with cryotherapy. Neuropathy seems to be related to direct contact between the solution and the epineurium.<\/jats:p>","DOI":"10.1111\/j.1601-0825.2012.01907.x","type":"journal-article","created":{"date-parts":[[2012,1,10]],"date-time":"2012-01-10T17:58:25Z","timestamp":1326218305000},"page":"548-557","source":"Crossref","is-referenced-by-count":35,"title":["Keratocystic odontogenic tumors and Carnoy\u2019s solution: results and complications assessment"],"prefix":"10.1111","volume":"18","author":[{"given":"O","family":"Ribeiro Junior","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AM","family":"Borba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CAF","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MM","family":"de Gouveia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FL","family":"Coracin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Guimar\u00e3es J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,2,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2010.10.010"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2000.110814"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0007-117X(75)90001-3"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(91)90211-T"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(97)90028-7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9785(80)80016-0"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.30.6.460"},{"key":"e_1_2_8_9_1","first-page":"129","article-title":"The primordial cyst. 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