{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:02:58Z","timestamp":1791918178267,"version":"4.3.4"},"reference-count":66,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,2,15]],"date-time":"2012-02-15T00:00:00Z","timestamp":1329264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Diseases"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p><jats:italic>Oral Diseases<\/jats:italic> (2012) <jats:bold>18,<\/jats:bold> 558\u2013567<\/jats:p><jats:p><jats:bold>Objective:\u2002<\/jats:bold> To compare the microbiota of endodontic infections in necrotic pulp from HIV\u2010negative and HIV\u2010positive subjects.<\/jats:p><jats:p><jats:bold>Materials and Methods:\u2002<\/jats:bold> Root canal samples from necrotic pulp were collected from 40 HIV\u2212 and 20 HIV+ subjects. Pulps were amplified using multiple displacement amplification (MDA). Then, checkerboard DNA\u2013DNA hybridization was employed to assess the levels of 107 microbial taxa. The percentage of DNA probe count and the percentage of teeth colonized by each test species were investigated. Significant differences between groups regarding proportions of taxa and prevalence of the test species were sought using the Mann\u2013Whitney test and the Chi\u2010square analysis, respectively.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> The most prevalent taxa detected were <jats:italic>Dialister pneumosintes<\/jats:italic>, <jats:italic>Stenotrophomonas maltophilia<\/jats:italic>, <jats:italic>Streptococcus sobrinus<\/jats:italic>, <jats:italic>Corynebacterium diphteriae<\/jats:italic>, and <jats:italic>Helicobacter pylori<\/jats:italic> among HIV\u2010 subjects and <jats:italic>D. pneumosintes<\/jats:italic>, <jats:italic>Prevotella tannerae<\/jats:italic>, <jats:italic>Porphyromonas gingivalis<\/jats:italic>, <jats:italic>Parvimonas micra<\/jats:italic>, <jats:italic>Prevotella nigrescens<\/jats:italic>, and <jats:italic>Corynebacterium diphtheriae<\/jats:italic> among HIV+ individuals. <jats:italic>D. pneumosintes<\/jats:italic>, <jats:italic>C. diphtheria<\/jats:italic>, and <jats:italic>C. albicans<\/jats:italic> were the most abundant species in the HIV\u2010 group, whereas the predominant taxa in HIV+ samples were <jats:italic>P. tannerae<\/jats:italic>, <jats:italic>D. pneumosintes<\/jats:italic> and <jats:italic>Olsenella uli<\/jats:italic>. <jats:italic>P. tannerae<\/jats:italic>, <jats:italic>O. uli<\/jats:italic>, <jats:italic>Veilonella dispar<\/jats:italic>, <jats:italic>Bacteroides fragilis<\/jats:italic>, and <jats:italic>Actinomyces meyeri<\/jats:italic> were significantly more abundant in HIV+ samples.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> There were significant differences in the prevalence and proportions of specific microbial taxa between HIV\u2212 and HIV+ individuals. The root canal microbiota may represent a reservoir of important oral and medical pathogens, mainly in HIV+ individuals.<\/jats:p>","DOI":"10.1111\/j.1601-0825.2012.01908.x","type":"journal-article","created":{"date-parts":[[2012,1,13]],"date-time":"2012-01-13T19:41:59Z","timestamp":1326483719000},"page":"558-567","source":"Crossref","is-referenced-by-count":17,"title":["Microbiologic profile of endodontic infections from HIV\u2212 and HIV+ patients using Multiple\u2010Displacement Amplification and Checkerboard DNA\u2010DNA Hybridization"],"prefix":"10.1111","volume":"18","author":[{"given":"LCN","family":"Brito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AP Ribeiro","family":"Sobrinho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RP","family":"Teles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SS","family":"Socransky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AD","family":"Haffajee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LQ","family":"Vieira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FRF","family":"Teles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,2,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.01034.x"},{"key":"e_1_2_7_3_1","first-page":"155","article-title":"Comparison of the success of root canal therapy in HIV\/AIDS patients and non\u2010infected controls","volume":"56","author":"Alley BS","year":"2008","journal-title":"Gen Dent"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-008-9153-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.57622"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02618-06"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.05.004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/10454411990100030701"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1999.tb01219.x"},{"key":"e_1_2_7_10_1","first-page":"262","article-title":"Anaerobic flora in endodontic infections","volume":"105","author":"Chaudhry R","year":"1997","journal-title":"Indian J Med Res"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2004.00845.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090185"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-302x.2000.150410.x"},{"key":"e_1_2_7_14_1","first-page":"700","article-title":"Oral lesions in infection with human immunodeficiency virus","volume":"83","author":"Coogan MM","year":"2005","journal-title":"Bull World Health Organ"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.082089499"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-005-0315-6"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2010.01765.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(83)90418-9"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-011-0391-6"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2005.01197.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060040"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2007.00411.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/898"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i41.5492"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00376.x"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2003.014704"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2009.01601.x"},{"issue":"1","key":"e_1_2_7_28_1","first-page":"1","article-title":"Microbiological examination of root canals and periapical tissues of human teeth. 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