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This global overview of SOT\/HSCT\u2010associated orofacial diseases is aimed at providing a practical instrument for the oral healthcare management of SOT\/HSCT recipients.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold>Literature search was made through MEDLINE. The associations between orofacial diseases and SOT\/HSCT were assessed using observational studies and case series and were classified into \u2018association\u2019, \u2018no association\u2019, and \u2018unclear association\u2019.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold>Lip\/oral cancers, drug\u2010induced gingival overgrowth (DIGO), infections, including hairy leukoplakia and, less frequently, post\u2010transplantation lymphoproliferative disorders (PTLDs) and oral lichenoid lesions of graft\u2010versus\u2010host disease (GVHD), were associated with SOT. Lip\/oral cancers, GVHD, mucositis, DIGO, infections and, less frequently, PTLDs were associated with HSCT. Associations of orofacial granulomatosis\u2010like lesions and oral mucosa\u2010associated lymphoid tissue\u2010type lymphoma with SOT, and of pyogenic granuloma and hairy leukoplakia with HSCT were unclear. Periodontal disease and dental caries were not associated with SOT\/HSCT. For none of the local treatments was there a strong evidence of effectiveness.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold>Solid organ transplant\/HSCT recipients are at risk of orofacial diseases. Adequate management of these patients alleviates local symptoms responsible for impaired eating, helps prevent systemic and lethal complications, and helps where dental healthcare has been neglected.<\/jats:p>","DOI":"10.1111\/j.1601-0825.2012.01925.x","type":"journal-article","created":{"date-parts":[[2012,3,5]],"date-time":"2012-03-05T19:49:16Z","timestamp":1330976956000},"page":"18-36","source":"Crossref","is-referenced-by-count":31,"title":["Orofacial diseases in solid organ and hematopoietic stem cell transplant 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