{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T20:14:40Z","timestamp":1775247280076,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,5,12]],"date-time":"2005-05-12T00:00:00Z","timestamp":1115856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p> <jats:italic>Background:<\/jats:italic> Hemangiomas and vascular malformations are the most common vascular lesions of infancy. Different lasers can be used for treatment. Nd:YAG laser photocoagulation is particularly effective because of its deep penetration into tissue.<\/jats:p><jats:p> <jats:italic>Patients and methods:<\/jats:italic> Thirty\u2010one patients, aged from three months to 18\u2005years, with voluminous hemangiomas and venous malformations were treated with a cw\u2010neodymium:YAG laser. The quartz fibre was used in percutaneous and intralesional technique. Long\u2010term follow\u2010up data were acquired by clinical control or a patient questionnaire for a maximal period of eight years. Twenty patients could be evaluated.<\/jats:p><jats:p> <jats:italic>Results:<\/jats:italic> In the group with hemangiomas (n\u2005=\u200515), three cases showed nearly complete remission (&gt;\u200390\u2003%), ten cases had a partial reduction in size (50\u200a\u2013\u200a90\u2003%), in one case there was stable disease and in one case tumor growth. In the group with venous malformations (n\u2005=\u20055) two cases showed an excellent response (&gt;\u200390\u2003%), one case a moderate response (25\u200a\u2013\u200a50\u2003%) and in two cases there was no improvement. Adverse effects included scars (40\u2003%), hyper\u2010 and hypopigmentation (23\u2003%), mild atrophy (20\u2003%) and a wrinkled texture (17\u2003%). After maximal reduction in size, 30\u2003% of the patients were not satisfied with the laser treatment outcome and elected surgical excision of the residual lesion.<\/jats:p><jats:p> <jats:italic>Conclusions:<\/jats:italic> The neodymium:yttrium aluminium garnet (Nd:YAG) laser with percutaneous or intralesional application technique is a valuable tool for selected patients with hemangiomas and venous malformations.<\/jats:p>","DOI":"10.1111\/j.1610-0387.2005.05723.x","type":"journal-article","created":{"date-parts":[[2005,5,12]],"date-time":"2005-05-12T09:27:57Z","timestamp":1115890077000},"page":"436-440","source":"Crossref","is-referenced-by-count":48,"title":["Neodymium\u2010YAG Laser for hemangiomas and vascular malformations \u2013 long term results"],"prefix":"10.1111","volume":"3","author":[{"given":"Heidi","family":"Ulrich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"B\u00e4umler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Hohenleutner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Landthaler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,5,12]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198203000-00002"},{"key":"e_1_2_7_3_2","unstructured":"WanerM SuenJY. A classification of congenital vascular lesions. In: Waner M Suen JY. Hemangiomas and vascular malformations of the head and neck. Wiley\u2010Liss New York 1999 p1\u200a\u2013\u200a12."},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(83)80043-8"},{"key":"e_1_2_7_5_2","first-page":"40","article-title":"Hemangiomas and vascular malformations","volume":"3","author":"Low DW","year":"1994","journal-title":"Semin Pediatr Surg"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199210000-00007"},{"key":"e_1_2_7_7_2","first-page":"631","article-title":"Management of alarming haemangiomas in infancy: a review of 25 cases","volume":"37","author":"Enjolras O","year":"1990","journal-title":"Paediatrics"},{"key":"e_1_2_7_8_2","unstructured":"TanOT. Management and treatment of benign cutaneous vascular lesions. 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