{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T04:59:19Z","timestamp":1770958759005,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,1,26]],"date-time":"2006-01-26T00:00:00Z","timestamp":1138233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2006,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p> <jats:italic>Background:<\/jats:italic> Radiotherapy plays an important role in the treatment of basal cell carcinoma of the face and head and achieves cure rates of 92\u201096 %. Different fractionation concepts of radiotherapy have been described.This study investigates the efficacy, as well as acute and chronic toxicity, of a slightly hypofractionated radiotherapy schedule.<\/jats:p><jats:p> <jats:italic>Patients and Methods:<\/jats:italic> 85 patients with 104 tumors underwent radiotherapy for basal cell carcinoma of the face and head. The radiotherapy schedule was 5\u00d73 Gray\/week up to a total dose of 57 Gray in 95 % of patients. Acute and late radiotherapy toxicity and cosmetic outcome were evaluated in long\u2010term follow\u2010up.<\/jats:p><jats:p> <jats:italic>Results:<\/jats:italic> No recurrence was observed. In 87 % of tumors, only low acute toxicity occurred at the end of radiotherapy. Late toxicity, if observed, was low in most patients. \u201cExcellent\u201d or \u201cgood\u201d cosmesis was achieved in 94 % of tumors at last follow\u2010up.<\/jats:p><jats:p> <jats:italic>Conclusions:<\/jats:italic> Our radiotherapy schedule achieves a very high local control rate and very good cosmetic and functional results.This fractionation can be recommended as a standardized radiotherapy treatment for basal cell carcinoma of the face and head.<\/jats:p>","DOI":"10.1111\/j.1610-0387.2006.05880.x","type":"journal-article","created":{"date-parts":[[2006,1,26]],"date-time":"2006-01-26T16:44:28Z","timestamp":1138293868000},"page":"124-130","source":"Crossref","is-referenced-by-count":36,"title":["Radiotherapy of basal cell carcinoma of the face and head: Importance of low dose per fraction on long\u2010term outcome"],"prefix":"10.1111","volume":"4","author":[{"given":"Thomas","family":"Olschewski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Bajor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Lang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugen","family":"Lang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael H.","family":"Seegenschmiedt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,26]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.73.863.538"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(05)70004-9"},{"key":"e_1_2_7_4_2","unstructured":"BartR KopfA Petratos M. 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