{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T12:02:10Z","timestamp":1717761730926},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,8,3]],"date-time":"2011-08-03T00:00:00Z","timestamp":1312329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:italic>Background:<\/jats:italic> Semipermanent henna tattoos containing para\u2010phenylenediamine (PPD) are a well\u2010known cause of severe contact dermatitis, mainly in children. Another relevant exposure source to PPD are hair dyes, which are increasingly used by children and have also been reported to cause intense facial and scalp dermatitis. German patch test guidelines for children recommend that PPD should only be tested in patients who have had a henna tattoo, and then at a reduced concentration of PPD 0.5 % for 24 hours.<\/jats:p><jats:p><jats:italic>Patients and methods:<\/jats:italic> We report on patch test results in four patients, three children and one adolescent, with a history of contact dermatitis to henna tattoos or hair dye. We used the recommended or even lower patch test concentrations of PPD with 24\u2010hours exposure in all patients.<\/jats:p><jats:p><jats:italic>Results and conclusion:<\/jats:italic> All patients showed very strong patch test reactions to PPD and cross\u2010reactions to related compounds even after dilution of PPD to as low as 0.05 %. Therefore, we suggest that in children with a history of allergic reactions to this compound, a titration test should be performed beginning at a concentration of maximal 0.05 %. This procedure has also been proposed previously based on a larger cases series in adults.<\/jats:p>","DOI":"10.1111\/j.1610-0387.2011.07756.x","type":"journal-article","created":{"date-parts":[[2011,8,3]],"date-time":"2011-08-03T22:22:07Z","timestamp":1312410127000},"page":"258-263","source":"Crossref","is-referenced-by-count":8,"title":["Severe allergic reactions to para\u2010phenylenediamine in children and adolescents: should the patch test concentration of PPD be changed?"],"prefix":"10.1111","volume":"10","author":[{"given":"Petra","family":"Spornraft\u2010Ragaller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"K\u00e4mmerer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus","family":"Gillitzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jochen","family":"Schmitt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,8,3]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/ajcd.2002.30466"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2002.470508.x"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1999.tb06102.x"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00702.x"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2007.06175.x"},{"key":"e_1_2_7_7_2","first-page":"393","article-title":"The identification of contact allergens by human assay. 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The maximization test: a procedure for screening and rating contact sensiti\u2010zers","volume":"47","author":"Kligman AM","year":"1966","journal-title":"J Invest Dermatol"},{"key":"e_1_2_7_8_2","first-page":"A1822","article-title":"Henna\/p\u2010Phenylendiamin\u2010Kontaktallergie: Fol\u2010genschwere Dermatosen nach Henna\u2010T\u00e4towierungen","volume":"98","author":"Hausen BM","year":"2001","journal-title":"Dt \u00c4rztebl"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08162.x"},{"key":"e_1_2_7_10_2","first-page":"423","article-title":"Contact dermatitis with henna tattoo","volume":"46","author":"Uzuner N","year":"2009","journal-title":"Indian Pediatr"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1470.2002.00219.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2008.00588.x"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06588.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2010.01843.x"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08644.x"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01000.x"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00498k.x"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2006.00746.x"},{"key":"e_1_2_7_19_2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1684\/ejd.2010.0808","article-title":"Contact allergy to hair colouring products. 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