{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T11:44:21Z","timestamp":1700048661246},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2012,6,28]],"date-time":"2012-06-28T00:00:00Z","timestamp":1340841600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p><jats:italic>Background:<\/jats:italic> Numerous studies have confirmed the short\u2010term effectiveness of 8\u2010methoxypsoralen bath PUVA therapy in patients with chronic palmoplantar dermatoses; however, little is known about long\u2010term results.<\/jats:p><jats:p><jats:italic>Patients and methods:<\/jats:italic> In this retrospective study we examined the long\u2010term results in 79 patients (mean age: 48 years) with chronic palmoplantar dermatoses who were treated with bath PUVA three times a week over an 8\u2010year period. A good clinical response (a reduction of more than 50% of the skin lesions) occurred after a mean of 23 treatments and a mean cumulative UVA dose of 39 J\/cm<jats:sup>2<\/jats:sup> in 51 patients (65%). In 2007 a questionnaire was sent to these 51 patients to assess the long\u2010term outcome.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> With bath PUVA treatment, the best results were found in patients with hyperkeratotic eczema (17\/22; 77% good clinical response) followed by patients with palmoplantar psoriasis (26\/41; 63%) and patients with dyshidrotic eczema (8\/16; 50%).<\/jats:p><jats:p>Thirty\u2010four patients (67%) answered the questionnaire after a mean follow\u2010up interval of 4.3 years (10\u201387 months). Among these patients, 36% reported an improved course of disease after PUVA therapy with reduced frequency and\/or intensity of the skin rash, and 29% of patients reported continued complete clearance. 79% of our patients reported a long\u2010term reduction in the use of topical corticosteroids during the follow\u2010up period (mean: 4.3 years). In addition, 67% of patients reported a lasting improvement in quality of life.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> These data show that bath PUVA may have a long\u2010term, beneficial influence on the course of disease in a majority of patients with recalcitrant chronic palmoplantar dermatoses.<\/jats:p>","DOI":"10.1111\/j.1610-0387.2012.07975.x","type":"journal-article","created":{"date-parts":[[2012,6,28]],"date-time":"2012-06-28T06:35:12Z","timestamp":1340865312000},"page":"814-818","source":"Crossref","is-referenced-by-count":2,"title":["Retrospective long\u2010term follow\u2010up in patients with chronic palmoplantar dermatoses after good response to bath PUVA therapy"],"prefix":"10.1111","volume":"10","author":[{"given":"Agnes","family":"Bretterklieber","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz J.","family":"Legat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelika","family":"Hofer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6,28]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-003-0659-2"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2009.03197.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08487.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2007.06378.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(89)70136-5"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546630600866442"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001050050119"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2006.00196.x"},{"key":"e_1_2_6_10_2","article-title":"PUVA\u2010Bad\u2010Therapie mit 8\u2010Methoxypsoralen zur Behandlung von palmoplantaren Dermatosen","author":"Kerscher M","year":"1994","journal-title":"H+G"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1992.tb14883.x"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.291.6499.861"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2007.01.045"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0353.2003.03595.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0781.2000.160107.x"},{"key":"e_1_2_6_16_2","first-page":"53","article-title":"Long term results of topical trioxsalen PUVA in lichen planus and nodular prurigo","volume":"120","author":"Karvonen J","year":"1985","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"issue":"1","key":"e_1_2_6_17_2","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2340\/00015555-0002","article-title":"Treatment of palmoplantar psoriasis with monochromatic excimer light (308 nm) versus cream PUVA","volume":"86","author":"Neumann NJ","year":"2006","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2009.00419.x"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1610-0387.2012.07975.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1610-0387.2012.07975.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:13:52Z","timestamp":1697415232000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1610-0387.2012.07975.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,28]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1111\/j.1610-0387.2012.07975.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1610-0387.2012.07975.x","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,28]]}}}