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In 2006 an anaphylaxis registry was established in German\u2010speaking countries. In the registry the triggers, circumstances, and treatment measures are collected from patients with anaphylaxis. However, the registry cannot supply epidemiological data like prevalence or incidence rates since the registration of cases is based on collaboration with allergy centers only. Similarly, other approaches to obtain data on the epidemiology of anaphylaxis are problematic given that allergic reactions of varying severity are covered by a number of codes in the ICD\u201010.<\/jats:p><jats:p>Research in the field of anaphylaxis is focused on the identification of risk factors. Several data indicate the relevance of co\u2010factors and augmentation factors in well\u2010defined patient groups. Among these factors physical activity, infection, alcohol and additives are relevant. In the future a unique coding system with a subtype analysis regarding the triggers and severity should help to provide data on the epidemiology of anaphylaxis. Furthermore the mechanisms of co\u2010factors and identification of biomarkers for risk assessment are important research areas for the future.<\/jats:p>","DOI":"10.1111\/j.1610-0387.2012.08045.x","type":"journal-article","created":{"date-parts":[[2012,11,26]],"date-time":"2012-11-26T15:09:20Z","timestamp":1353942560000},"page":"44-50","source":"Crossref","is-referenced-by-count":9,"title":["Causes and risk factors for 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