{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T12:53:46Z","timestamp":1782564826462,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","issue":"s434","license":[{"start":{"date-parts":[[2007,1,2]],"date-time":"2007-01-02T00:00:00Z","timestamp":1167696000000},"content-version":"vor","delay-in-days":2345,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2000,8]]},"abstract":"<jats:p>Allergy and asthma are common diseases today. Ways to stop the ongoing increase in incidence of these diseases are highly desired. In this review the scientific basis for allergy and asthma prevention is discussed. <jats:italic>Results:<\/jats:italic> Although secondary preventive measures are generally regarded as important, the views regarding the possibility of primary prevention vary. There is today only weak evidence that breastfeeding may reduce the risk of developing allergy, and if it does the effect is limited in degree and duration. There is some evidence that prolonged breastfeeding reduces the risk of developing asthma, at least in allergy\u2010risk infants. There is also some evidence indicating that withholding solid foods in children at risk may have a beneficial effect. A dose\u2010dependent risk of becoming sensitized to house dust mite and pet animal allergens has clearly been shown, but to what extent this sensitization is combined with asthma or clinical allergy is less well elucidated. Passive smoking increases the risk of wheezing problems and the indoor environment in damp houses seems to act synergistically with passive smoke.<\/jats:p><jats:p> <jats:italic>Conclusion:<\/jats:italic> Primary prevention is rarely possible, but the risk of developing asthma and allergy may to some extent be reduced by taking certain measures, such as avoidance of tobacco smoke and damp houses. Breastfeeding seems to reduce the risk of wheezing, but as allergy\u2010preventive measures, breastfeeding and avoiding pet animals have only marginal effects.<\/jats:p>","DOI":"10.1111\/j.1651-2227.2000.tb03099.x","type":"journal-article","created":{"date-parts":[[2010,8,7]],"date-time":"2010-08-07T04:03:41Z","timestamp":1281153821000},"page":"71-75","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Is prevention of allergy and asthma possible?"],"prefix":"10.1111","volume":"89","author":[{"given":"T","family":"Foucard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.46.8.549"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.52.2.161"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1997.tb09021.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1971.tb02447.x"},{"issue":"10","key":"e_1_2_1_6_2","first-page":"32","article-title":"The environment and sensitisation to allergens in early childhood","volume":"8","author":"Bj\u00f6rkst\u00e9n B.","year":"1997","journal-title":"Pediatr Allergy Immunol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.1990.tb00003.x"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1997.tb14898.x"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)91742-X"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.68.6.724"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00209530"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1983.tb09738.x"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.86.4.541"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.1993.tb00088.x"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.77.1.4"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90181-4"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(97)80009-7"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)91260-F"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.1999.00534.x"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.1990.tb00015.x"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.1998.tb00296.x"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0668.1998.00003.x"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10081774"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.1999.00753.x"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.101.2.e8"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70284-8"},{"key":"e_1_2_1_27_2","first-page":"16","volume-title":"Luften vi andas inomhus. Inomhusmilj\u00f6ns betydelse f\u00f6r allergi och annan \u00f6verk\u00e4nslighet. Vetenskaplig kunskapssammanst\u00e4llning","author":"Sundell J","year":"1994"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1998.tb03859.x"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.63.5.473"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(87)80161-6"},{"key":"e_1_2_1_31_2","first-page":"265","article-title":"Studies of prevalence of Japanese cedar pollinosis among the residents in a densely cultivated area","volume":"58","author":"Ishizaki T","year":"1987","journal-title":"Ann Allergy"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1651-2227.2000.tb03099.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1651-2227.2000.tb03099.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T21:52:21Z","timestamp":1695765141000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1651-2227.2000.tb03099.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8]]},"references-count":30,"journal-issue":{"issue":"s434","published-print":{"date-parts":[[2000,8]]}},"alternative-id":["10.1111\/j.1651-2227.2000.tb03099.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1651-2227.2000.tb03099.x","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,8]]},"assertion":[{"value":"2007-01-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}