{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:23:35Z","timestamp":1790735015420,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2010,10,13]],"date-time":"2010-10-13T00:00:00Z","timestamp":1286928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim:\u2002<\/jats:bold> To evaluate the efficacy of various echocardiographic markers in predicting a patent ductus arteriosus (PDA) in need of treatment.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Forty\u2010five preterm infants with a mean (SD) gestational age of 27.7 (1.9) weeks underwent echocardiography at a postnatal age of 24\u2003\u00b1\u20036 and 72\u2003\u00b1\u20036\u2003h. Four echocardiographic markers were studied: ductus diameter, ductal flow Doppler curves, the left atrial to aortic root (LA\/Ao) ratio and Doppler pixels representing ductal shunting.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Twenty\u2010eight infants had a PDA with a detectable left\u2010to\u2010right shunt. Of these, 12 (43%) were treated for a shunt through the PDA. Ductal diameter was the most accurate echocardiographic marker when it came to predicting a significant shunt, with a sensitivity of 89%, a specificity of 70%, a positive likelihood ratio of 2.97 and a negative likelihood ratio of 0.16 at the age of 72\u2003h. The efficacy of the method at 72\u2003h of age was 84%. The corresponding efficacy of the pulsatile Doppler curve was 72%, percentage of green colour pixels 63% and the LA\/Ao ratio 53%.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Ductus diameter appears to be the most important variable in determining the need for therapeutic intervention for PDA in preterm infants.<\/jats:p>","DOI":"10.1111\/j.1651-2227.2010.02027.x","type":"journal-article","created":{"date-parts":[[2010,9,27]],"date-time":"2010-09-27T15:04:22Z","timestamp":1285599862000},"page":"231-235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Echocardiographic prediction of patent ductus arteriosus in need of therapeutic intervention"],"prefix":"10.1111","volume":"100","author":[{"given":"S","family":"Harling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Hansen\u2010Pupp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Baigi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Pesonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,10,13]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80247-3"},{"key":"e_1_2_7_3_2","first-page":"1095","article-title":"[Patent ductus arteriosus in neonatal intensive care]","volume":"18","author":"Baptista MJ","year":"1999","journal-title":"Rev Port Cardiol"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(09)90044-0"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1986.tb10393.x"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2001.047"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70172-9"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/fn.77.1.F36"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.50.4.821"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2008.09.017"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2003.027698"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780050606"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2006.00179.x"},{"key":"e_1_2_7_14_2","first-page":"279","volume-title":"Textbook of clinical decisions and lab use","author":"Galen RS","year":"1982"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(01)00124-4"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/fn.70.2.F112"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200009073431001"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2007.00455.x"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1159\/000457546"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)83391-8"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199609000-00011"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2001.110528"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.1994.tb00689.x"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1651-2227.2010.02027.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1651-2227.2010.02027.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T14:11:56Z","timestamp":1697379116000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1651-2227.2010.02027.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,13]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["10.1111\/j.1651-2227.2010.02027.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1651-2227.2010.02027.x","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,13]]},"assertion":[{"value":"2010-10-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}