{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T20:17:27Z","timestamp":1784751447824,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,9,23]],"date-time":"2011-09-23T00:00:00Z","timestamp":1316736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim:\u2002<\/jats:bold> To investigate the association between perinatal risk factors and neonatal complications and early oculo\u2010motor development in very preterm infants.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Perinatal risk factors were identified, and the potential association with early oculo\u2010motor development was evaluated by measuring smooth pursuit eye movements (SP) at 2 and 4\u2003months\u2019 corrected age (CA) in a population of very preterm infants born in Uppsala County 2004\u20132007 (n\u2003=\u2003113).<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Among the 15 tested factors, eight showed significant association in univariate analysis with lower levels of SP at 4\u2003months\u2019 CA, namely administration of prenatal corticosteroids, gestational age, birthweight, bronchopulmonary dysplasia, retinopathy of prematurity, periventricular leukomalacia, intraventricular haemorrhage &gt;grade 2, and persistent ductus arteriosus. At 2\u2003months\u2019 CA, only retinopathy of prematurity &gt;stage 2 was associated with lower levels of SP. When all factors significant in the univariate tests were included in multiple regressions aimed to assess each factor\u2019s independent relation to SP, periventricular leukomalacia was the only significant independent factor. When adding 2\u20135 of the significant factors using multiple regression analysis, the levels of SP became lower.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Perinatal risk factors were associated with lower levels of SP. This could be interpreted as delayed or disturbed development of normal oculomotor ability.<\/jats:p>","DOI":"10.1111\/j.1651-2227.2011.02449.x","type":"journal-article","created":{"date-parts":[[2011,8,31]],"date-time":"2011-08-31T23:29:31Z","timestamp":1314833371000},"page":"164-171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Development of smooth pursuit eye movements in very preterm born infants: 3. 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