{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:40:01Z","timestamp":1792842001644,"version":"4.5.0"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,1,9]],"date-time":"2012-01-09T00:00:00Z","timestamp":1326067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim:\u2002<\/jats:bold> To predict early nasal continuous positive airway pressure failure within the first 2\u2003h after birth in preterm infants.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Patient and respiratory support variables significantly associated with continuous positive airway pressure failure in the first 72\u2003h after birth were identified in a cohort of preterm infants &lt;30\u2003weeks gestation. Using multivariable logistic regression analysis, risk estimates for early nasal continuous positive airway pressure failure were calculated.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> From 182 infants included, 62(34%) failed early nasal continuous positive airway pressure. Birth weight \u2264800\u2003g, male gender and a fraction of inspired oxygen &gt;0.25 at 1 and 2\u2003h of age were significantly associated with early nasal continuous positive airway pressure failure. Combining these variables in a logistic regression model provided a minimal risk estimate for failure of 0.04[0.01\u20130.23] (female &gt;800\u2003g, FiO<jats:sub>2<\/jats:sub>\u2003\u2264\u20030.25 at 1, and 2\u2003h) and maximal estimate of 0.92[0.44\u20130.99] (male \u2264800\u2003g, FiO<jats:sub>2<\/jats:sub>\u2003&gt;\u20030.25 at 1 and 2\u2003h).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Combining gender, birth weight and the fraction of inspired oxygen at 1 and 2\u2003h of age allows for a better and more individualized prediction of early nasal continuous positive airway pressure failure in preterm infants less than 30\u2003weeks gestation.<\/jats:p>","DOI":"10.1111\/j.1651-2227.2011.02558.x","type":"journal-article","created":{"date-parts":[[2011,12,10]],"date-time":"2011-12-10T08:17:29Z","timestamp":1323505049000},"page":"374-379","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Early prediction of nasal continuous positive airway pressure failure in preterm infants less than 30\u2003weeks gestation"],"prefix":"10.1111","volume":"101","author":[{"given":"Anne P","family":"De Jaegere","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna H","family":"van der Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Cant\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton H","family":"van Kaam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,9]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"CD007836","article-title":"Animal derived surfactant extract for treatment of respiratory distress syndrome","volume":"2","author":"Seger N","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_3_2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1542\/peds.79.1.26","article-title":"Is chronic lung disease in low birth weight infants preventable? 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