{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T17:09:10Z","timestamp":1763572150911},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,3,24]],"date-time":"2012-03-24T00:00:00Z","timestamp":1332547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Paediatrica"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Aim:\u2002<\/jats:bold> To explore associations with fractures reported in a tertiary neonatal intensive care unit (NICU).<\/jats:p><jats:p><jats:bold>Method:\u00a0<\/jats:bold> Babies admitted to NICU from 1998 to 2007 in Cardiff, UK, with fractures during admission were identified. Clinical information was extracted from inpatient records. Results were reported as median (ranges).<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Seventy\u2010one fractures were recorded in 27 (boys\u2003=\u200316) infants with a gestational age of 28 (23.6\u201340.4) weeks and birthweight of 920\u2003g (485\u20134875). Fractures were recognized at 57 (1\u2013128) days of age. Neonates with fractures without clear aetiologies (n\u2003=\u200317) were more preterm (p\u2003&lt;\u20030.001), were born lighter (p\u2003&lt;\u20030.001), required multiple medical interventions, were more commonly osteopenic (p\u2003&lt;\u20030.001), had fractures detected later (p\u2003&lt;\u20030.001) and had more posterior rib fractures (p\u2003=\u20030.009). Rib fractures were detected later than other sites (p\u2003=\u20030.002). Associations with rib fractures included osteopenia (p\u2003=\u20030.04), longer oxygen therapy (p\u2003=\u20030.018), length on total parental nutrition (p\u2003=\u20030.03), later achievement of full enteral feeds (p\u2003=\u20030.038), sepsis (p\u2003=\u20030.038) and surgical procedures (p\u2003=\u20030.004). Posterior rib fractures were more common in babies born more preterm (25.1 vs. 29.4\u2003weeks, p\u2003=\u20030.003) and requiring diuretics (p\u2003=\u20030.027).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Fractures in premature infants are associated with a variety of predisposing factors. Clinicians evaluating the cause of rib and multiple fractures in preterm neonates shortly after discharge need to take these factors into consideration.<\/jats:p>","DOI":"10.1111\/j.1651-2227.2012.02640.x","type":"journal-article","created":{"date-parts":[[2012,2,25]],"date-time":"2012-02-25T19:20:55Z","timestamp":1330197655000},"page":"587-590","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Fractures in a tertiary Neonatal Intensive Care Unit in Wales"],"prefix":"10.1111","volume":"101","author":[{"given":"Christina","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Mott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin","family":"Warner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,24]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.105.4.e48"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.TA.0000068992.01030.A8"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/01241398-198801000-00010"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199702000-00023"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/01202412-198909030-00012"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2005.12.007"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.106120"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.301.6745.225"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70127-3"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2007.067"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.136853"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002470050073"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.200.3.8756936"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/fn.86.2.F82"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002470050773"},{"key":"e_1_2_8_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-1383(00)00234-5"}],"container-title":["Acta Paediatrica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1651-2227.2012.02640.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1651-2227.2012.02640.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:40:47Z","timestamp":1697416847000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1651-2227.2012.02640.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,24]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1651-2227.2012.02640.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1651-2227.2012.02640.x","archive":["Portico"],"relation":{},"ISSN":["0803-5253","1651-2227"],"issn-type":[{"value":"0803-5253","type":"print"},{"value":"1651-2227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,24]]},"assertion":[{"value":"2012-03-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}