{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T05:42:57Z","timestamp":1709358177106},"reference-count":48,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,11,1]],"date-time":"2006-11-01T00:00:00Z","timestamp":1162339200000},"content-version":"vor","delay-in-days":31,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p>Diuretic renal scintigraphy is commonly used in human medicine to differentiate obstructive from nonobstructive pyelectasia. In order to determine normal parameters,<jats:sup>99m<\/jats:sup>Tc\u2010DTPA renal scintigraphy was performed twice in 20 healthy adult Mongrel dogs. Each dog was injected with either 3.0\u2003mg\/kg furosemide or an equivalent volume of saline 4.5\u2003min following injection of the radiopharmaceutical. The following parameters were evaluated: (1) global and individual glomerular filtration rate (GFR); (2) time of peak (TOP) of the time\u2013activity curve (TAC); (3) shape of the TAC; (4) individual kidney excretion half\u2010time (<jats:italic>T<\/jats:italic><jats:sub>1\/2<\/jats:sub>); (5) proportion of maximum activity measured at end of study (8\u2003min); (6) time of onset; and (7) duration of the effect of the diuretic. Most TAC in the diuretic renography group showed a steep drop in the curve following administration of the diuretic compared with a gradual slope in the saline control group. There was a statistically significant difference in<jats:italic>T<\/jats:italic><jats:sub>1\/2<\/jats:sub>between the control renograms (median 10.25\u2003min, range 4.41\u201318.07\u2003min) and the diuretic renograms (median 4.16\u2003min, range 3.62\u20135.90\u2003min). There was a statistically significant difference in percentage maximum activity between the control renograms (median 65.25%, range 48.27\u201393.68%) and the diuretic renograms (median 48.54%, range 35.64\u201358.76%). Median time of onset of the diuretic effect was 1.10\u2003min (0.20\u20132.40\u2003min), and median duration was 0.83\u2003min (0.30\u20132.35\u2003min).<\/jats:p>","DOI":"10.1111\/j.1740-8261.2006.00194.x","type":"journal-article","created":{"date-parts":[[2006,11,2]],"date-time":"2006-11-02T15:48:47Z","timestamp":1162482527000},"page":"602-608","source":"Crossref","is-referenced-by-count":11,"title":["DIURETIC RENAL SCINTIGRAPHY IN NORMAL DOGS"],"prefix":"10.1111","volume":"47","author":[{"given":"SILKE","family":"HECHT","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GREGORY B.","family":"DANIEL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SALLY K.","family":"MITCHELL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,11]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"235","volume-title":"Thomson's special veterinary pathology","author":"Confer AW","year":"2001"},{"key":"e_1_2_7_3_2","first-page":"397","article-title":"Lesions of the renal pelvis and proximal ureter in various nephro\u2010urological conditions","volume":"36","author":"Felkai CS","year":"1995","journal-title":"an ultrasonographic study"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1994.tb00177.x"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365598309179787"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2000.00563.x"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.1980.tb04502.x"},{"key":"e_1_2_7_8_2","first-page":"932","article-title":"Clinical, clinicopathologic, radiographic, and ultrasonographic abnormalities in cats with ureteral calculi","volume":"226","author":"Kyles AE","year":"2005","journal-title":"163 cases (1984\u20132002)"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2004.03.008"},{"key":"e_1_2_7_10_2","first-page":"1576","article-title":"Antegrade pyelography for suspected ureteral obstruction in cats","volume":"222","author":"Adin CA","year":"2003","journal-title":"11 cases (1995\u20132001)"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(98)50080-0"},{"key":"e_1_2_7_12_2","first-page":"572","article-title":"Renal nuclear medicine","volume":"40","author":"Daniel GB","year":"1999","journal-title":"a review"},{"key":"e_1_2_7_13_2","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.2460\/ajvr.1999.60.11.1383","article-title":"Effect of partial ureteral obstruction on results of renal scintigraphy in dogs","volume":"60","author":"Barthez PY","year":"1999","journal-title":"Am J Vet Res"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2003.tb00481.x"},{"key":"e_1_2_7_15_2","first-page":"765","article-title":"Diuretic renography in the evaluation of neonatal hydronephrosis","volume":"150","author":"Chung S","year":"1993","journal-title":"is it reliable?"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002590050354"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02985962"},{"key":"e_1_2_7_18_2","first-page":"153","article-title":"Idiopathic hydronephrosis\u2014the diuresis renogram","volume":"121","author":"O'Reilly PH","year":"1979","journal-title":"a new non-invasive method of assessing equivocal pelvioureteral junction obstruction"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)55042-9"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.2001.02213.x"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)66192-7"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0094-0143(05)70011-2"},{"key":"e_1_2_7_23_2","first-page":"1872","article-title":"Consensus on diuresis renography for investigating the dilated upper urinary tract. 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