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In this retrospective study of 37 dogs with histologically confirmed intracranial disease, we investigated whether histogram analysis of quantitative apparent diffusion coefficients (ADC) can differentiate specific disease processes. Disease categories included: meningiomas, glial cell tumors, choroid plexus tumors, pituitary tumors, inflammatory brain diseases, acute nonhemorrhagic infarcts, chronic nonhemorrhagic infarcts, and hemorrhagic infarcts. A wide range of ADC value distributions were identified within the disease groups, and there were overlapping ADC values between most groups. Low ADC values indicating restricted diffusion of water were identified in acute nonhemorrhagic infarcts as expected, but were also seen in meningiomas, glial cell tumors, and granulomatous meningoencephalitis. Based on this preliminary data it is unlikely that singular quantitative ADC values can be used to determine the histological type of canine intracranial disease.<\/jats:p>","DOI":"10.1111\/j.1740-8261.2010.01764.x","type":"journal-article","created":{"date-parts":[[2010,11,11]],"date-time":"2010-11-11T17:03:26Z","timestamp":1289495006000},"page":"142-148","source":"Crossref","is-referenced-by-count":36,"title":["MAGNETIC RESONANCE IMAGING APPARENT DIFFUSION COEFFICIENTS FOR HISTOLOGICALLY CONFIRMED INTRACRANIAL LESIONS IN 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