{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T00:28:30Z","timestamp":1782520110058,"version":"3.54.5"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,8,10]],"date-time":"2011-08-10T00:00:00Z","timestamp":1312934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:p>A delay in imaging following intravenous contrast medium administration has been recommended to reduce misdiagnoses. However, the normal variation of contrast enhancement in dogs following a delay has not been characterized. Contrast\u2010enhanced MR imaging of 22 dogs was assessed, in terms of identification of normal anatomic structures, to investigate the variation associated with 10\u2010min delay between contrast medium administration and imaging. All dogs had a normal brain MR imaging study and unremarkable cerebrospinal fluid. Specific regions of interest were assessed both objectively, using computer software, and subjectively using three observers. Mean contrast enhancement &gt;10% was seen in the pituitary gland, choroid plexus, meninges, temporal muscle, trigeminal nerve, and the trigeminal nerve root. Structures with an active blood\u2013brain barrier had minimal contrast enhancement (&lt;6%). Enhancing structures had significantly more contrast enhancement at <jats:italic>t<\/jats:italic>=1\u2003min vs. <jats:italic>t<\/jats:italic>=10\u2003min, except in temporal muscle, the trigeminal nerve and the trigeminal nerve root. Interobserver agreement was moderate to good in favor of the initial postcontrast T1\u2010weighted (T1w) sequence. The observers found either no difference or poor agreement in identification of the nonvascular structures. Intraobserver agreement was very good with all vascular structures and most nonvascular structures. A degree of meningeal enhancement was a consistent finding. The initial acquisition had higher enhancement characteristics and observer agreement for some structures; however, contrast\u2010to\u2010noise was comparable in the delayed phase or not significantly different. We provide baseline references and suggest that the initial T1w postcontrast sequence is preferable but not essential should a delayed postcontrast T1w sequence be performed.<\/jats:p>","DOI":"10.1111\/j.1740-8261.2011.01847.x","type":"journal-article","created":{"date-parts":[[2011,8,10]],"date-time":"2011-08-10T15:17:08Z","timestamp":1312989428000},"page":"611-618","source":"Crossref","is-referenced-by-count":18,"title":["EFFECT OF DELAYED ACQUISITION TIMES ON GADOLINIUM\u2010ENHANCED MAGNETIC RESONANCE IMAGING OF THE PRESUMABLY NORMAL CANINE BRAIN"],"prefix":"10.1111","volume":"52","author":[{"given":"STEPHEN","family":"JOSLYN","sequence":"first","affiliation":[{"name":"Small Animal Hospital University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MARTIN","family":"SULLIVAN","sequence":"additional","affiliation":[{"name":"Small Animal Clinical Sciences University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ROSA","family":"NOVELLAS","sequence":"additional","affiliation":[{"name":"Facultad de Veterinaria Universidad Aut\u00f3noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NICOLA","family":"BRENNAN","sequence":"additional","affiliation":[{"name":"Small Animal Hospital University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GILL","family":"CAMERON","sequence":"additional","affiliation":[{"name":"Small Animal Hospital University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GAWAIN","family":"HAMMOND","sequence":"additional","affiliation":[{"name":"Small Animal Clinical Sciences University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,8,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.147.3.6342034"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.142.3.619"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880070104"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.156.3.4040643"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004424-198511000-00011"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.1.2399335"},{"key":"e_1_2_6_8_1","first-page":"1013","article-title":"Time\u2010dependent changes in image contrast in brain tumors after gadolinium\u2013DTPA","volume":"7","author":"Sch\u00f6rner W","year":"1986","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910190217"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00343790"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.143.2.215"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2000.tb00419.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2005.00069.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2010.01785.x"},{"key":"e_1_2_6_15_1","first-page":"1","article-title":"Inter\u2010rater reliability: dependency on trait prevalence and marginal homogeneity","volume":"2","author":"Gwet K.","year":"2002","journal-title":"Stat Methods Inter\u2010Rater Reliability Assessment Ser"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(96)80339-4"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(97)00215-3"},{"key":"e_1_2_6_19_1","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1111\/j.1939-1676.2003.tb02514.x","article-title":"Dynamic computed tomography of the pituitary gland in dogs with pituitary\u2010dependent hyperadrenocorticism","volume":"17","author":"van der Vlugt\u2010Meijer RH","year":"2003","journal-title":"J Vet Int Med"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2000.tb00423.x"},{"issue":"4","key":"e_1_2_6_21_1","first-page":"1501","article-title":"The capillary bed in the choroid plexus of the lateral ventricles: a study of luminal casts","author":"Motti ED","year":"1986","journal-title":"Scanning Electron Microsc"},{"key":"e_1_2_6_22_1","first-page":"209","article-title":"Arterial supply and venous drainage of the choroid plexus of the human lateral ventricle in the prenatal period as revealed by vascular corrosion casts and SEM","volume":"67","author":"Zag\u00f3rska\u2010Swiezy K","year":"2008","journal-title":"Folia Morphol (Warsz)"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2002.tb00435.x"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2008.00042.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0221-0363(05)81507-0"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1076-6332(96)80002-X"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.162.1.8273651"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.211.1.r99mr25257"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2010.01789.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2008.00375.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.152.4.825"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.10169"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20535"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2009.01533.x"},{"key":"e_1_2_6_35_1","first-page":"1317","article-title":"MR imaging of the trigeminal ganglion, nerve, and the perineural vascular plexus: normal appearance and variants with correlation to cadaver specimens","volume":"24","author":"Williams LS","year":"2003","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2010.01713.x"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.3950\/jibiinkoka.97.684"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199508000-00017"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1740-8261.2011.01847.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1740-8261.2011.01847.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T08:45:22Z","timestamp":1698741922000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1740-8261.2011.01847.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,10]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["10.1111\/j.1740-8261.2011.01847.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1740-8261.2011.01847.x","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,10]]}}}