{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T02:15:57Z","timestamp":1776132957025,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,6,15]],"date-time":"2012-06-15T00:00:00Z","timestamp":1339718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:p>Golden retriever and<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>abrador retriever muscular dystrophy are inherited progressive degenerative myopathies that are used as models of<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>uchenne muscular dystrophy in man. Thoracic lesions were reported to be the most consistent radiographic finding in golden retriever dogs in a study where radiographs were performed at a single\u2010time point. Muscular dystrophy worsens clinically over time and longitudinal studies in dogs are lacking. Thus our goal was to describe the thoracic abnormalities of golden retriever and<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>abrador retriever dogs, to determine the timing of first expression and their evolution with time. To this purpose, we retrospectively reviewed 390 monthly radiographic studies of 38 golden retrievers and six<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>abrador retrievers with muscular dystrophy. The same thoracic lesions were found in both golden and<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>abrador retrievers. They included, in decreasing frequency, flattened and\/or scalloped diaphragmatic shape (43\/44), pulmonary hyperinflation (34\/44), hiatal hernia (34\/44), cranial pectus excavatum (23\/44), bronchopneumonia (22\/44), and megaesophagus (14\/44). The last three lesions were not reported in a previous radiographic study in golden retriever dogs. In all but two dogs the thoracic changes were detected between 4 and 10 months and were persistent or worsened over time. Clinically, muscular dystrophy should be included in the differential diagnosis of dogs with a combination of these thoracic radiographic findings.<\/jats:p>","DOI":"10.1111\/j.1740-8261.2012.01948.x","type":"journal-article","created":{"date-parts":[[2013,3,12]],"date-time":"2013-03-12T16:22:24Z","timestamp":1363105344000},"page":"492-500","source":"Crossref","is-referenced-by-count":16,"title":["AGE\u2010RELATED THORACIC RADIOGRAPHIC CHANGES IN GOLDEN AND LABRADOR RETRIEVER MUSCULAR DYSTROPHY"],"prefix":"10.1111","volume":"53","author":[{"given":"Anne\u2010Sophie","family":"Bedu","sequence":"first","affiliation":[{"name":"The Unit\u00e9 de radiologie Universit\u00e9 de Paris Est Ecole Nationale v\u00e9t\u00e9rinaire d'Alfort 94700 Maisons\u2010Alfort France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien J.","family":"Labruy\u00e8re","sequence":"additional","affiliation":[{"name":"Vet CT Specialists Ltd St John's Innovation Centre Cowley Road CB40WS Cambridge 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