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In advanced cases, cats will display prominent facial features and upper airway congestion secondary to bony and soft tissue proliferation. The purpose of this study was to describe <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> characteristics of soft tissues and skull bones in six cats with presumed acromegaly and to compare findings with those observed in 12 unaffected cats. In the five acromegalic cats with <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> evidence of a pituitary tumor, frontal bone thickness was greater than age\u2010matched controls with and without a history of upper airway disease. These five cats also had evidence of soft tissue accumulation in the nasal cavity, sinuses, and pharynx. One cat with insulin\u2010resistant diabetes mellitus, elevated <jats:styled-content style=\"fixed-case\">IGF<\/jats:styled-content>\u20101, and a normal pituitary size did not have evidence of frontal bone thickening or upper airway congestion.<\/jats:p>","DOI":"10.1111\/j.1740-8261.2012.01957.x","type":"journal-article","created":{"date-parts":[[2013,3,12]],"date-time":"2013-03-12T16:22:24Z","timestamp":1363105344000},"page":"535-539","source":"Crossref","is-referenced-by-count":24,"title":["CT AND MRI EVALUATION OF SKULL BONES AND SOFT TISSUES IN SIX CATS WITH PRESUMED ACROMEGALY VERSUS 12 UNAFFECTED CATS"],"prefix":"10.1111","volume":"53","author":[{"given":"Anthony J.","family":"Fischetti","sequence":"first","affiliation":[{"name":"From the Department of Diagnostic Imaging, Animal Medical Center New York NY 10065"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Gisselman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark E.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,6,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1990.tb00897.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.216.1765"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb03041.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2004.09.002"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-008-0104-8"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/jfms.2000.0091"},{"key":"e_1_2_8_8_1","first-page":"889","article-title":"Serum insulin\u2010like growth factor\u20101 in cats with diabetes mellitus and acromegaly","volume":"21","author":"Berg RI","year":"2007","journal-title":"J Vet Intern Med"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1255020"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3171\/2010.7.FOCUS10152"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100107455"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.03.014"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.12.003"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2011.01821.x"},{"key":"e_1_2_8_15_1","first-page":"376","volume-title":"Canine and feline endocrinology and reproduction","author":"Feldman EC","year":"1996"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2003.tb00455.x"},{"key":"e_1_2_8_17_1","first-page":"206","article-title":"Hyperostosis frontalis interna: case report and review of the literature","volume":"34","author":"She R","year":"2004","journal-title":"Ann Clin Lab Sci"},{"key":"e_1_2_8_18_1","first-page":"830","article-title":"Diagnosis of acromegaly on cranial computed tomography","volume":"18","author":"Barmeir EP","year":"1982","journal-title":"Isr J Med Sci"},{"key":"e_1_2_8_19_1","first-page":"796","article-title":"Evaluation of temporal bone computed tomography and paranasal sinuses magnetic resonance images in acromegalic patients","volume":"31","author":"Zatonski T","year":"2010","journal-title":"Neuro Endocrinol Lett"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2008.04.007"}],"container-title":["Veterinary Radiology &amp; Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1740-8261.2012.01957.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1740-8261.2012.01957.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T14:15:52Z","timestamp":1698675352000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1740-8261.2012.01957.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,15]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,9]]}},"alternative-id":["10.1111\/j.1740-8261.2012.01957.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1740-8261.2012.01957.x","archive":["Portico"],"relation":{},"ISSN":["1058-8183","1740-8261"],"issn-type":[{"value":"1058-8183","type":"print"},{"value":"1740-8261","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,15]]}}}