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Of these, 17 were confirmed thyroid carcinoma, while six were initially misdiagnosed. These included four carotid body tumors, one para\u2010esophageal abscess, and one undifferentiated squamous cell carcinoma. Thyroid carcinomas occurred in older dogs without evidence of sex predilection, and were more often unilateral. All were large, heterogeneous, moderately to strongly vascularized, and most commonly contained areas of dystrophic mineralization and\/or fluid accumulations. On <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>, thyroid carcinomas appeared hyperintense compared to surrounding musculature in all imaging sequences used, while on <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> they had a lower attenuation value than normal thyroid gland tissue. Histologically confirmed tumor capsule disruption with invasion of the surrounding structures was most commonly detected with <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. Palpation was not an accurate predictor of locally invasive vs. well\u2010encapsulated masses. Computed tomography had the highest specificity (100%) and <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> had the highest sensitivity (93%) in diagnosing thyroid carcinoma, while ultrasound had considerably lower results. We conclude that ultrasound is adequate for use as a screening tool for dogs with suspected thyroid carcinoma, but recommend either <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> for preoperative diagnosis and staging.<\/jats:p>","DOI":"10.1111\/j.1740-8261.2012.01966.x","type":"journal-article","created":{"date-parts":[[2013,3,12]],"date-time":"2013-03-12T16:01:12Z","timestamp":1363104072000},"page":"61-70","source":"Crossref","is-referenced-by-count":47,"title":["COMPARISON BETWEEN CLINICAL, ULTRASOUND, <scp>CT<\/scp>, <scp>MRI<\/scp>, AND PATHOLOGY FINDINGS IN DOGS PRESENTED FOR SUSPECTED THYROID CARCINOMA"],"prefix":"10.1111","volume":"54","author":[{"given":"Olivier","family":"Taeymans","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Cummings School of Veterinary Medicine Tufts University  North Grafton MA 01536"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique G.","family":"Penninck","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Cummings School of Veterinary Medicine Tufts University  North Grafton MA 01536"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel M.","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Cummings School of Veterinary Medicine Tufts University  North Grafton MA 01536"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,9,18]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"1761","volume-title":"Textbook of veterinary internal medicine","author":"Mooney CT","year":"2010"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2007.tb03008.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2007.03.008"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1994.tb02047.x"},{"key":"e_1_2_7_6_1","first-page":"219","volume-title":"Canine and feline endocrinology and reproduction","author":"Feldman EC","year":"2004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/107327480601300203"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2004.09.003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(98)50085-X"},{"key":"e_1_2_7_10_1","first-page":"86","volume-title":"Canine and feline endocrinology and reproduction","author":"Feldman EC","year":"2004"},{"key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/S0030-6665(20)30522-3","article-title":"Thyroid and parathyroid gland pathology. 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