{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T21:04:17Z","timestamp":1772831057124,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,10,14]],"date-time":"2012-10-14T00:00:00Z","timestamp":1350172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Radiology Ultrasound"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>The aims of this prospective study were to describe the normal sonographic size and appearance of the feline spleen, and to test effects of sevoflurane anesthesia and blood collection on sonographic characteristics. Sonographic evaluations were performed in 60 healthy blood donor cats prior to anesthesia and blood collection (baseline), after anesthesia induction, after completion of blood collection while under anesthesia, and 7\u201310 days after blood collection. Transverse sonographic images of the splenic mid\u2010body were made. Splenic height, width, cross\u2010sectional area, echogenicity relative to the left renal cortex, and echotexture were recorded. Height, width, and cross\u2010sectional area were compared across time periods using linear\u2010mixed effects models.<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>olm's method was applied to adjust for multiplicity and control the overall Type 1 error rate at \u03b1 = 0.05. Normal transverse sonographic splenic measurements (mean \u00b1 standard deviation) at baseline were: height 8.2 \u00b1 1.4 mm; width 26.7 \u00b1 4.4 mm; and<jats:styled-content style=\"fixed-case\">CSA<\/jats:styled-content>1.6 \u00b1 0.5 cm<jats:sup>2<\/jats:sup>. While there were statistically significant differences in splenic height, width, and cross\u2010sectional area after sevoflurane anesthesia and\/or blood collection, differences were of low magnitude. The spleen was diffusely homogenous and subjectively isoechoic or mildly hyperechoic relative to the left renal cortex. In 77% of castrated male cats, the spleen was isoechoic to the left renal cortex. We conclude that sevoflurane anesthesia and blood donation do not subjectively alter splenic dimensions, echogenicity and echotexture in normal cats.<\/jats:p>","DOI":"10.1111\/j.1740-8261.2012.01990.x","type":"journal-article","created":{"date-parts":[[2013,3,12]],"date-time":"2013-03-12T16:46:58Z","timestamp":1363106818000},"page":"168-175","source":"Crossref","is-referenced-by-count":25,"title":["EFFECT OF SEVOFLURANE ANESTHESIA AND BLOOD DONATION ON THE SONOGRAPHIC APPEARANCE OF THE SPLEEN IN 60 HEALTHY CATS"],"prefix":"10.1111","volume":"54","author":[{"given":"Shona L.","family":"Reese","sequence":"first","affiliation":[{"name":"Small Animal Clinical Sciences University of Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa J.","family":"Zekas","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Sciences The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Cristina","family":"Iazbik","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Sciences The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Lehman","sequence":"additional","affiliation":[{"name":"Center for Biostatistics The Ohio State University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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