{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T02:20:48Z","timestamp":1768011648536,"version":"3.49.0"},"reference-count":42,"publisher":"Wiley","issue":"s2","license":[{"start":{"date-parts":[[2011,3,2]],"date-time":"2011-03-02T00:00:00Z","timestamp":1299024000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Maternal &amp; Child Nutrition"],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Maternal mental health (MMH) problems are a major public health concern with adverse consequences for women, their offspring and families. Intake of long\u2010chain polyunsaturated fatty acids, especially the n\u20103 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid, which are found predominantly in cold water fish, has been associated with a range of mental health outcomes and may improve MMH. The demands for these fatty acids are increased during pregnancy and lactation, and may influence MMH as they are integral parts of cell membranes especially in the brain and play a role in physiological processes such as membrane fluidity and neurotransmitter function. Observational studies and intervention trials that have examined the role of fatty acids and MMH disorders especially post\u2010partum depression (PPD) were identified using Pubmed and have been reviewed. Only three well\u2010designed large prospective studies were identified; these studies examined the relationship between dietary intakes of n\u20103 fatty acids and fish during pregnancy, and found limited evidence of an association with PPD. Several intervention trials (<jats:italic>n<\/jats:italic>\u2003=\u20038) have been done but generally suffer from small sample size and vary in terms of the study subject characteristics and timing, duration and dosage of the intervention. The results are mixed, but one recently completed large trial found no evidence of benefit among women who received DHA during pregnancy. Few studies have been conducted in developing countries, and gaps remain on the influence of other nutrient deficiencies, genetic polymorphisms that influence n\u20103 fatty acid synthesis and total fatty acid intake.<\/jats:p>","DOI":"10.1111\/j.1740-8709.2011.00312.x","type":"journal-article","created":{"date-parts":[[2011,3,5]],"date-time":"2011-03-05T18:52:11Z","timestamp":1299351131000},"page":"99-111","source":"Crossref","is-referenced-by-count":13,"title":["Fatty acid status and maternal mental health"],"prefix":"10.1111","volume":"7","author":[{"given":"Usha","family":"Ramakrishnan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,3,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/14767050701209560"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/84.6.1308"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2008.04.009"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954422408998620"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28313"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2008.01.003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2005.10.009"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26811E"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2008.12.008"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2008.10.003"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26692G"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2007.12.228"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2005.00660.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31819d6a57"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(01)00374-3"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2007.032"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/10284150410001710438"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPM.2008.001"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2009.06.368"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161209789909683"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2003.275"},{"key":"e_1_2_7_23_1","unstructured":"LucasM. MirzaeF. ReillyE. PanA. WillettW. KawachiI.(2010)Dietary omega\u20103 and omega\u20106 intake and the risk of clinical depression. Results from the nurses health study. Poster presented at ISSFAL 2010 (page 57)."},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1507"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.10148"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2009.00229.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291706008701"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2007.10.013"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.200900157"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8709.2010.00254.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26692F"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2008.26692F"},{"key":"e_1_2_7_33_1","doi-asserted-by":"crossref","first-page":"S100","DOI":"10.1177\/15648265100312S203","article-title":"Docosahexaenoic acid supplementation during pregnancy and gestational age and size at birth: randomized, double\u2010blind, placebo controlled trial in Mexico","volume":"31","author":"Ramakrishnan U.","year":"2010","journal-title":"Food and Nutrition Bulletin"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/00048670701827267"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2007.12.011"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980007668578"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-007-0671-x"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2008.00941.x"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.27552"},{"key":"e_1_2_7_40_1","unstructured":"SuK.&ChenC.T.(2010)Fish\u2010oil supplementation of maternal rats prevents depletion of maternal brain regional docosahexanoic acid levels and has a post\u2010partum anxiolytic effect. Poster presented at ISSFAL 2010 (page 155)."},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v69n0418"},{"key":"e_1_2_7_42_1","unstructured":"World Health Organization (WHO)(2008)Maternal mental health and child health and development in low and middle income countries. Report of the WHO meeting."},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.108.096156"}],"container-title":["Maternal &amp; Child Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1740-8709.2011.00312.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1740-8709.2011.00312.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T01:42:27Z","timestamp":1694569347000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1740-8709.2011.00312.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,2]]},"references-count":42,"journal-issue":{"issue":"s2","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["10.1111\/j.1740-8709.2011.00312.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1740-8709.2011.00312.x","archive":["Portico"],"relation":{},"ISSN":["1740-8695","1740-8709"],"issn-type":[{"value":"1740-8695","type":"print"},{"value":"1740-8709","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,2]]}}}