{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:11:34Z","timestamp":1790115094754,"version":"4.0.1"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,1,23]],"date-time":"2006-01-23T00:00:00Z","timestamp":1137974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:p><jats:bold>Objectives:\u2002<\/jats:bold> To determine whether the 3\u2010monthly application of chlorhexidine (CHX)\u2013thymol varnish is an effective method of controlling plaque and gingivitis in a group of institutionalised elderly as a complement to their usual oral hygiene practices.<\/jats:p><jats:p><jats:bold>Design:\u2002<\/jats:bold> A 6\u2010month double\u2010blind clinical trial.<\/jats:p><jats:p><jats:bold>Setting:\u2002<\/jats:bold> Two residential homes in Almer\u00eda (Spain).<\/jats:p><jats:p><jats:bold>Participants:\u2002<\/jats:bold> Fifty\u2010six dentate subjects aged above 64\u2003years who completed the 6\u2010month study.<\/jats:p><jats:p><jats:bold>Intervention:\u2002<\/jats:bold> The study subjects were randomly assigned to one of two groups (Cervitec<jats:sup>\u00ae<\/jats:sup> or placebo). Varnishes were applied twice in the first week of the study and were applied again a month later and every 3\u2003months until the end of the study. The patients continued with their usual oral hygiene practices throughout the study.<\/jats:p><jats:p><jats:bold>Measurement:\u2002<\/jats:bold> Plaque index and gingival index scores were determined at baseline and after 1, 3 and 6\u2003months.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Treatment with Cervitec<jats:sup>\u00ae<\/jats:sup> varnish had a statistically significant effect overtime on the gingival index score (<jats:italic>p<\/jats:italic>\u2003=\u20030.029), but not on the plaque index score (<jats:italic>p<\/jats:italic>\u2003=\u20030.651). The groups did not significantly differ in reductions in plaque or gingival index scores between baseline and 1, 3 or 6\u2003months.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> According to these results, Cervitec<jats:sup>\u00ae<\/jats:sup>, a CHX\u2013thymol varnish, does not appear to reduce plaque and gingivitis by a 3\u2010monthly application in the institutionalised elderly with poor oral hygiene. Wider studies are required to investigate different varnishing protocols in geriatric populations.<\/jats:p>","DOI":"10.1111\/j.1741-2358.2006.00085.x","type":"journal-article","created":{"date-parts":[[2006,1,23]],"date-time":"2006-01-23T17:35:58Z","timestamp":1138037758000},"page":"43-47","source":"Crossref","is-referenced-by-count":11,"title":["Efficacy of chlorhexidine\u2013thymol varnish (Cervitec<sup>\u00ae<\/sup>) against plaque accumulation and gingival inflammation in a geriatric population"],"prefix":"10.1111","volume":"23","author":[{"given":"Javier","family":"Clavero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Baca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00aa","family":"Paloma Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano J","family":"Valderrama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,1,23]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1993.tb00719.x"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.1984.tb00358.x"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1987.tb00968.x"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(91)90161-5"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.1994.tb01116.x"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2002.290101.x"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/00220345920710090701"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02679961"},{"key":"e_1_2_7_10_2","first-page":"46","article-title":"Effects of a chlorhexidine varnish on the gingival status of adolescents","volume":"62","author":"Valente MI","year":"1996","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_7_11_2","first-page":"399","article-title":"Chlorhexidine varnishes prevent gingivitis in adolescents","volume":"67","author":"Bretz WA","year":"2000","journal-title":"J Dent Child"},{"key":"e_1_2_7_12_2","first-page":"231","article-title":"Chlorhexidine release by dentine after varnish treatment","volume":"27","author":"Arends J","year":"1993","journal-title":"Caries Res"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0909-8836.1998.eos106106.x"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016356408993968"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016356309011240"},{"key":"e_1_2_7_16_2","volume-title":"Oral Health Surveys: Basic Methods","author":"Word Health Organization","year":"1997"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-5712(02)00045-3"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00365.x"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/000163599429066"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-595X.2002.tb00879.x"},{"key":"e_1_2_7_21_2","first-page":"1582","article-title":"Mutans streptococci, oral hygiene and caries in an adult Swedish population","volume":"68","author":"Salonen L","year":"1990","journal-title":"J Dent Res"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.1994.tb01124.x"}],"container-title":["Gerodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1741-2358.2006.00085.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1741-2358.2006.00085.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T20:56:35Z","timestamp":1696971395000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1741-2358.2006.00085.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1,23]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,3]]}},"alternative-id":["10.1111\/j.1741-2358.2006.00085.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1741-2358.2006.00085.x","archive":["Portico"],"relation":{},"ISSN":["0734-0664","1741-2358"],"issn-type":[{"value":"0734-0664","type":"print"},{"value":"1741-2358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,1,23]]}}}