{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T12:10:26Z","timestamp":1773317426166,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,5,22]],"date-time":"2012-05-22T00:00:00Z","timestamp":1337644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p><jats:italic>doi: 10.1111\/j.1741\u20102358.2011.00512.x<\/jats:italic><\/jats:p><jats:p><jats:bold>Leishmaniasis with oral mucosa involvement<\/jats:bold><\/jats:p><jats:p><jats:bold>Introduction:\u2002<\/jats:bold> The term leishmaniasis comprises a group of diseases caused by different protozoan species of the genus <jats:italic>Leishmania<\/jats:italic>. There are three main clinical forms of leishmaniasis: visceral, cutaneous and mucocutaneous. Exclusive involvement of the mucosa is very rare.<\/jats:p><jats:p><jats:bold>Objectives:\u2002<\/jats:bold> To present a case of mucocutaneous leishmaniasis in an elderly patient, discuss the clinical presentation, diagnostic process and treatment emphasizing the distinctions from other granulomatous lesions.<\/jats:p><jats:p><jats:bold>Case report:\u2002<\/jats:bold> A 71\u2010year\u2010old male presenting with a symptomatic lesion on the hard and soft palate, which had developed over a period of 6 months was evaluated. The oral exam revealed a lesion with multiple ulcerated nodules on the hard and soft palate extending to the oropharynx. The diagnostic hypothesis was chronic infectious disease (paracoccidioidomycose, tuberculosis and leishmaniasis) or squamous cell carcinoma. Histopathological, histochemical and immunohistochemical analysis were performed. A chest x\u2010ray revealed a normal pulmonary pattern. The Montenegro skin test was positive. The definitive diagnosis was leishmaniasis with exclusive oral manifestation and the patient was treated with liposomal amphotericin.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Localized oral mucosa leishmaniasis is an uncommon event in an immunocompetent patient. Dentists play an important role in the diagnosis of oral leishmaniasis, which has systemic repercussions.<\/jats:p>","DOI":"10.1111\/j.1741-2358.2011.00512.x","type":"journal-article","created":{"date-parts":[[2012,5,22]],"date-time":"2012-05-22T11:17:57Z","timestamp":1337685477000},"source":"Crossref","is-referenced-by-count":13,"title":["Leishmaniasis with oral mucosa involvement"],"prefix":"10.1111","volume":"29","author":[{"given":"Ana C. A.","family":"Pellicioli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco A. T.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoel Sant\u2019ana","family":"Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pantelis V.","family":"Rados","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoela D.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,5,22]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-777X.62863"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1586\/eri.10.19"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2009000600015"},{"key":"e_1_2_4_5_2","unstructured":"World Health Organization (WHO).Magnitude of the Problem.http:\/\/www.who.int\/leishmaniasis\/burden\/magnitude\/burden_magnitude\/en\/print.html. Accessed in October 2010."},{"key":"e_1_2_4_6_2","unstructured":"SINAN Sistema de Informa\u00e7\u00e3o de Agravos de Notifica\u00e7\u00e3o.http:\/\/portal.saude.gov.br\/portal\/saude\/default.cfm. Accessed in October 2010."},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822010000400012"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652008000500007"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2009.11.004"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2007.07.008"},{"key":"e_1_2_4_11_2","first-page":"E281","article-title":"Localized Leishmaniasis of the oral mucosa. A report of three cases","volume":"12","author":"Garc\u00eda de Marcos JA","year":"2007","journal-title":"Med Oral, Patol Oral Cir Bucal"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-777X.68528"},{"key":"e_1_2_4_13_2","first-page":"45","article-title":"Aspectos histopatol\u00f3gicos e ultra\u2010estruturais da leishmaniose cut\u00e2nea difusa (LCD)","volume":"79","author":"Bittencourt AL","year":"2009","journal-title":"Gaz Med Bahia"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(86)90243-9"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91945-7"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/168.3.699"},{"key":"e_1_2_4_17_2","first-page":"820","article-title":"Leishmaniasis in a heart transplant patient","volume":"11","author":"Golino A","year":"1992","journal-title":"J Heart Lung Transplant"}],"container-title":["Gerodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1741-2358.2011.00512.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1741-2358.2011.00512.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T06:50:30Z","timestamp":1697352630000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1741-2358.2011.00512.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,22]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["10.1111\/j.1741-2358.2011.00512.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1741-2358.2011.00512.x","archive":["Portico"],"relation":{},"ISSN":["0734-0664","1741-2358"],"issn-type":[{"value":"0734-0664","type":"print"},{"value":"1741-2358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,22]]}}}