{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T17:13:55Z","timestamp":1776446035375,"version":"3.51.2"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2011,8,24]],"date-time":"2011-08-24T00:00:00Z","timestamp":1314144000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p><jats:italic>doi: 10.1111\/j.1741\u20102358.2011.00549.x<\/jats:italic>\n          \u2028\n          <jats:bold>The efficacy of a topical gel with triester glycerol oxide in denture\u2010related mucosal injuries<\/jats:bold><\/jats:p><jats:p><jats:bold>Objective:\u2002<\/jats:bold> The efficacy of a topical gel with triester glycerol oxide for treating ulcerations related to new complete dentures was studied and compared with a placebo gel.<\/jats:p><jats:p><jats:bold>Materials and methods:\u2002<\/jats:bold> Fifty edentulous patients were enrolled in this double\u2010blind clinical study. All subjects received new maxillary and mandibular complete dentures and were recalled 1, 3 and 7\u2003days after denture placement. Twenty\u2010five subjects received topical gel with triester glycerol oxide (TGO), and 25 subjects received topical gel without TGO. At each visit, pain and discomfort with the new dentures was assessed, and at the last visit, healing of ulcerations was also graded by a clinician. Subjects also graded the gel\u2019s taste, smell and ease of use.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Specifically, there was no statistically significant difference in ulcer healing (<jats:italic>p\u2003<\/jats:italic>&gt;<jats:italic>\u2003<\/jats:italic>0.05), ratings of smell, taste and ease of use (<jats:italic>p\u2003<\/jats:italic>&gt;<jats:italic>\u2003<\/jats:italic>0.05) or pain and discomfort scores (<jats:italic>p\u2003<\/jats:italic>&gt;<jats:italic>\u2003<\/jats:italic>0.05). However, within\u2010group differences were observed in pain and discomfort scores between follow\u2010up sessions (<jats:italic>p\u2003<\/jats:italic>=<jats:italic>\u2003<\/jats:italic>0.01 for all comparisons).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Clinically, TGO gel is not effective in the treatment of mucosal injuries occurring following placement of complete dentures.<\/jats:p>","DOI":"10.1111\/j.1741-2358.2011.00549.x","type":"journal-article","created":{"date-parts":[[2011,8,31]],"date-time":"2011-08-31T22:59:42Z","timestamp":1314831582000},"source":"Crossref","is-referenced-by-count":15,"title":["The efficacy of a topical gel with triester glycerol oxide in denture\u2010related mucosal 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