{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:52:04Z","timestamp":1780534324527,"version":"3.54.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,5,22]],"date-time":"2012-05-22T00:00:00Z","timestamp":1337644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p><jats:italic>doi: 10.1111\/j.1741\u20102358.2012.00624.x<\/jats:italic><\/jats:p><jats:p><jats:bold>Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report<\/jats:bold><\/jats:p><jats:p><jats:bold>Background:\u2002<\/jats:bold> Drug\u2010influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine. Its occurrence in both dentate and edentulous regions of oral cavity is poorly understood.<\/jats:p><jats:p><jats:bold>Objectives:\u2002<\/jats:bold> This report highlights clinical and histological description, aetiology and management of gingival overgrowth in a partially edentulous (non\u2010denture wearer) 60\u2010year\u2010old female patient with epilepsy on phenytoin and phenobarbital drugs from past 7\u2003years.<\/jats:p><jats:p><jats:bold>Materials and methods:\u2002<\/jats:bold> Patient\u2019s intraoral examination revealed lobulated and fibrotic consistency gingival overgrowth around teeth and on partially edentulous ridges of upper and lower arches along with generalised tooth mobility. Under medical consultation, full mouth extraction, surgical excision of overgrowth followed by complete denture rehabilitation and replacement of combination drugs with sodium valproate were accomplished.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Histologically, the lesion showed fibro\u2010epithelial hyperplasia. Clinical results after 6\u2003months demonstrated almost complete resolution of gingival overgrowth.<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The findings of present case suggest that gingival overgrowth can occur even in partially edentulous ridges (not exposed to denture wear) that could be due to persistence of gingival overgrowth, which may not resolve completely following tooth extraction or occurs because of incorporation of specific subpopulation of gingival fibroblasts in alveolar ridge mucosa.<\/jats:p>","DOI":"10.1111\/j.1741-2358.2012.00624.x","type":"journal-article","created":{"date-parts":[[2012,5,22]],"date-time":"2012-05-22T11:17:57Z","timestamp":1337685477000},"source":"Crossref","is-referenced-by-count":8,"title":["Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report"],"prefix":"10.1111","volume":"29","author":[{"given":"Kunaal","family":"Dhingra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shobha","family":"Prakash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.7"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1996.tb02072.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.1998.tb00269.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.1999.tb00224.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1999.tb00175.x"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.10.1424"},{"key":"e_1_2_6_8_2","first-page":"54","article-title":"Hyperplasia of the oral mucosa in an edentulous epileptic","volume":"59","author":"Dallas B","year":"1963","journal-title":"N Z Dent J"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(78)90144-5"},{"key":"e_1_2_6_10_2","first-page":"114","article-title":"Gingival hyperplasia of an edentulous alveolar ridge in an epileptic\u2010a case report","volume":"84","author":"Darling MR","year":"1988","journal-title":"N Z Dent J"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(92)90366-I"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1992.0190"},{"key":"e_1_2_6_13_2","first-page":"408","article-title":"Phenobarbital\u2010induced gingival overgrowth? 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