{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T01:40:47Z","timestamp":1771378847385,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,11,26]],"date-time":"2012-11-26T00:00:00Z","timestamp":1353888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Congenital Anomalies"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>We report a case of osteogenesis imperfecta (OI) (OMIM166210) type II, in which a prenatal diagnosis was made by three\u2010dimensional computed tomography (3D\u2010CT). Subsequent molecular analysis revealed a recurrent, heterozygous mutation in <jats:italic>COL1A2<\/jats:italic>. Fetal CT is a powerful tool for visualizing the fetal skeleton and can provide a definitive diagnosis of fetal skeletal dysplasias; however, whether or not its employment for prenatal diagnosis is warranted in terms of fetal radiation risks remains controversial, both medically and ethically. Based on our experience, we review the current state of fetal CT for the diagnosis of skeletal dysplasias, with a discussion of the relevant literature.<\/jats:p>","DOI":"10.1111\/j.1741-4520.2011.00346.x","type":"journal-article","created":{"date-parts":[[2011,10,13]],"date-time":"2011-10-13T16:18:29Z","timestamp":1318522709000},"page":"203-206","source":"Crossref","is-referenced-by-count":6,"title":["Prenatal diagnosis of osteogenesis imperfecta type II by three\u2010dimensional computed tomography: The current state of fetal computed tomography"],"prefix":"10.1111","volume":"52","author":[{"given":"Yoshika","family":"Akizawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gen","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomonobu","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Takagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yayoi","family":"Kawamichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Matsui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kayoko","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000089042"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4001"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0223(200101)21:1<68::AID-PD994>3.0.CO;2-3"},{"key":"e_1_2_5_5_1","unstructured":"International Commission on Radiological Protection.2000.Pregnancy and Medical Radiation. ICRP International Commission on Radiological Protection Stockholm Sweden. [Cited 1 Aug 2001.] Available from URL:http:\/\/www.icrp.org\/docs\/ICRP_84_Pregnancy_s.pps."},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20429"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-007-0568-0"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-010-0010-7"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3302199"},{"key":"e_1_2_5_10_1","unstructured":"OMIM OSTEOGENESIS IMPERFECTA TYPEIIA. [Cited 9 June 2011.] Available from URL:http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?itool=genetests_disease_docsum&Cmd=Link&LinkName=genetests_omim&IdsFromResult=200399."},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000235884"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/2.12.2175"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1113"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0223(199707)17:7<670::AID-PD113>3.0.CO;2-8"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-003-0771-8"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000170092"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000322212"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.172.3.10063887"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.545903"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2010.01324.x"}],"container-title":["Congenital Anomalies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1741-4520.2011.00346.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1741-4520.2011.00346.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T15:15:55Z","timestamp":1697382955000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1741-4520.2011.00346.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,26]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1111\/j.1741-4520.2011.00346.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1741-4520.2011.00346.x","archive":["Portico"],"relation":{},"ISSN":["0914-3505","1741-4520"],"issn-type":[{"value":"0914-3505","type":"print"},{"value":"1741-4520","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,26]]}}}