{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T20:47:02Z","timestamp":1760820422334},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2012,1,30]],"date-time":"2012-01-30T00:00:00Z","timestamp":1327881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["International Wound Journal"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:p>Pressure mapping alone insufficiently describes tissue health. Comprehensive, quantitative non invasive assessment is crucial. Interface pressures (IPs) and transcutaneous blood gas levels [transcutaneous tissue oxygen (T<jats:sub>c<\/jats:sub>PO<jats:sub>2<\/jats:sub>)] were simultaneously assessed over both ischia and the sacrum to investigate the hypotheses: (i) tissue oxygenation decreases with sustained applied pressure; (ii) tissue oxygen and IP are inversely correlated in loaded soft tissues; (iii) multisite assessments are unnecessary because healthy individuals are symmetrical. Measurements were taken at 5\u2010minute intervals for 20 minutes in both sitting and supine lying for a cohort of 20 able\u2010bodied adults. There were no statistically significant changes over time for either variable in 96% of timepoint comparisons. Specifically, no significant differences were seen between 10 and 20 minutes in either position. These findings imply that a 10\u2010minute assessment can reliably indicate tissue health and that tissue may adapt to applied load over time. No statistically significant correlations between T<jats:sub>c<\/jats:sub>PO<jats:sub>2<\/jats:sub> and IP were observed. However, the left and right ischia were significantly different for both variables in supine lying (<jats:italic>P<\/jats:italic> &lt; 0\u00b7001) and for sitting IP (<jats:italic>P<\/jats:italic> &lt; 0\u00b7010). Thus, even in this healthy cohort, postural symmetry was not observed and should not be assumed for other populations with restricted mobility. If a multisite technique cannot be used, repeated tissue health assessments must use the same anatomic location.<\/jats:p>","DOI":"10.1111\/j.1742-481x.2011.00935.x","type":"journal-article","created":{"date-parts":[[2012,1,30]],"date-time":"2012-01-30T15:30:07Z","timestamp":1327937407000},"page":"656-664","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Physiological measurements of tissue health; implications for clinical practice"],"prefix":"10.1111","volume":"9","author":[{"given":"Jennifer H","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chester H","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kath M","family":"Bogie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,30]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-28804-X_4"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00129334-200107000-00015"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/sc.1995.31"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2008.08.212"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1179\/107902610X12923394765616"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/0003319707300353"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-197510000-00012"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1682\/JRRD.1990.04.0141"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000068243.63203.A8"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2001.90.6.2231"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2000.9164"},{"key":"e_1_2_9_13_2","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1080\/10790268.2007.11754584","article-title":"Measuring tissue perfusion during pressure relief maneuvers: insights into preventing pressure ulcers.","volume":"30","author":"Makhsous M","year":"2007","journal-title":"J Spinal Cord Med"},{"key":"e_1_2_9_14_2","first-page":"202","article-title":"Transcutaneous oxygen tension in subjects with tetraplegia with and without pressure ulcers: a preliminary report.","volume":"36","author":"Liu MH","year":"1999","journal-title":"J Rehabil Res Dev"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.1682\/JRRD.2008.12.0164"},{"key":"e_1_2_9_16_2","doi-asserted-by":"crossref","first-page":"198","DOI":"10.3233\/THC-2007-15303","article-title":"How do normals move during prolonged wheelchair\u2010sitting?","volume":"15","author":"Linder\u2010Ganz E","year":"2007","journal-title":"Technol Health Care"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1682\/JRRD.2003.11.0469"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1682\/JRRD.2008.12.0164"},{"key":"e_1_2_9_19_2","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1080\/10790268.2007.11754584","article-title":"Measuring tissue perfusion during pressure relief maneuvers: insights into preventing pressure ulcers.","volume":"30","author":"Makhsous M","year":"2007","journal-title":"J Spinal Cord Med"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2005.11.020"},{"key":"e_1_2_9_21_2","unstructured":"URLhttp:\/\/www.tekscan.com\/body\u2010pressure\u2010measurement[accessed on 20 July 2011]."},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.math.2010.06.005"},{"key":"e_1_2_9_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10926-008-9123-6"},{"key":"e_1_2_9_24_2","volume-title":"Applied longitudinal data analysis.","author":"Davidian M.","year":"2006"},{"key":"e_1_2_9_25_2","doi-asserted-by":"crossref","DOI":"10.1007\/b97287","volume-title":"Statistical methods for the analysis of repeated measurements.","author":"Davis CS.","year":"2002"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2003.50038"},{"key":"e_1_2_9_27_2","first-page":"34","article-title":"Are all pressure ulcers the result of deep tissue injury? 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