{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T01:40:59Z","timestamp":1720316459670},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,11,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Hypercoagulable state is a complex condition with an abnormal propensity for thrombosis. The consequences of it due to thrombosis of veins and arteries are the most common cause of sickness.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>The present study is a report of a case describing penis necrosis after circumcision and evaluation of hypercoagulable state as a reason of it.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Nine-year-old boy referred from another hospital with the sequelae of the penile ischemia with discoloration of the penis after traditional circumcision.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The ischemic event developed 3 weeks after circumcision. Priapism that was treated with needed glandulocavernous shunt initially developed following circumcision. All values of routine blood count and blood biochemical analysis were within normal limits. Further, hematologic studies revealed that there might be a hypercoagulable state as a result of lower protein S level.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Circumcision is a common procedure frequently performed in many communities around the world. Although it is seen as an easy procedure and performed even by unauthorized medical stuff, it is not complication-free. Severe penile necrosis after circumcision should be treated on an individual basis, necessitating different techniques. Hypercoagulable state should be concerned and evaluated in such a complication. In short, circumcision has to be done by specialists who can handle such serious complications.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1111\/j.1743-6109.2011.02415.x","type":"journal-article","created":{"date-parts":[[2011,8,2]],"date-time":"2011-08-02T20:42:18Z","timestamp":1312317738000},"page":"3236-3240","source":"Crossref","is-referenced-by-count":7,"title":["Penile Necrosis due to Priapism Developed After Circumcision in a Patient with Protein S Deficiency"],"prefix":"10.1093","volume":"8","author":[{"given":"Halil I.","family":"Canter","sequence":"first","affiliation":[{"name":"Department of Plastic, Reconstructive and Aesthetic Surgery, Acibadem University School of Medicine, Acibadem Bakirkoy Hospital , Bakirkoy, Istanbul , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enis R.","family":"Coskuner","sequence":"additional","affiliation":[{"name":"Department of Urology, Acibadem University School of Medicine, Acibadem Bakirkoy Hospital , Bakirkoy, Istanbul , Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,11,1]]},"reference":[{"key":"2023010704074038800_bb0010","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/02724939992743","article-title":"Complications of traditional male circumcision","volume":"19","author":"Ahmed","year":"1999","journal-title":"Ann Trop Paediatr"},{"key":"2023010704074038800_bb0015","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/S0022-3476(05)80346-4","article-title":"Arterial thrombosis and protein S deficiency","volume":"121","author":"Horowitz","year":"1992","journal-title":"J Pediatr"},{"key":"2023010704074038800_bb0020","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1055\/s-2007-1002683","article-title":"Neonatal purpura fulminans due to homozygous protein C or protein S deficiency","volume":"16","author":"Marlar","year":"1990","journal-title":"Semin Thromb Hemost"},{"key":"2023010704074038800_bb0025","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/00000637-200101000-00021","article-title":"Bilateral lower extremity thrombosis in a patient with protein S deficiency","volume":"46","author":"Vargel","year":"2001","journal-title":"Ann Plast Surg"},{"key":"2023010704074038800_bb0030","first-page":"167","article-title":"Hypercoagulable states","volume":"34","author":"Bertina","year":"1997","journal-title":"Semin Hematol"},{"key":"2023010704074038800_bb0035","first-page":"171","article-title":"Risk factors for venous thrombosis: Prevalence, risk and interaction","volume":"34","author":"Rosendaal","year":"1997","journal-title":"Semin Hematol"},{"key":"2023010704074038800_bb0040","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1111\/j.1743-6109.2009.01625.x","article-title":"Priapism: Pathogenesis, epidemiology, and management","volume":"7","author":"Broderick","year":"2010","journal-title":"J Sex Med"},{"key":"2023010704074038800_bb0045","doi-asserted-by":"crossref","first-page":"3572","DOI":"10.1111\/j.1743-6109.2010.02062.x","article-title":"Summary of the recommendations on sexual dysfunctions in men","volume":"7","author":"Montorsi","year":"2010","journal-title":"J Sex Med"},{"key":"2023010704074038800_bb0050","first-page":"337","article-title":"Priapism and activated protein C resistance","volume":"15","author":"Guichard","year":"2005","journal-title":"Prog Urol"},{"key":"2023010704074038800_bb0055","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1111\/j.1751-553X.2007.00963.x","article-title":"Stuttering priapism complicating warfarin therapy in a patient with protein deficiency","volume":"30","author":"Abu Sham'a","year":"2008","journal-title":"Int J Lab Hematol"},{"key":"2023010704074038800_bb0060","first-page":"701","article-title":"Recurrent priapism in sickle cell trait with protein S deficiency","volume":"58","author":"Rehman","year":"2008","journal-title":"J Pak Med Assoc"},{"key":"2023010704074038800_bb0065","first-page":"7991","article-title":"Diagnosis and treatment of venous thromboembolism in children and adolescents on behalf of the subcommittee on perinatal haemostasis of scientific and standardization committee of ISTH","volume":"74","author":"David","year":"1995","journal-title":"Thromb Haemost"},{"key":"2023010704074038800_bb0070","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1056\/NEJM199111283252207","article-title":"Treatment of homozygous protein C deficiency and neonatal purpura fulminans with purified protein C concentrate","volume":"325","author":"Dreyfub","year":"1991","journal-title":"N Engl J Med"},{"key":"2023010704074038800_bb0075","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1097\/00006534-200211000-00049","article-title":"Necrosis of the toe resulting from protein S deficiency","volume":"110","author":"Terzioglu","year":"2002","journal-title":"Plast Reconstr Surg"},{"key":"2023010704074038800_bb0080","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1055\/s-0038-1642558","article-title":"The frequency of the type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis","volume":"59","author":"Gladson","year":"1988","journal-title":"Thromb Haemost"}],"container-title":["The Journal of Sexual Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1743609515333294?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1743609515333294?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/8\/11\/3236\/48476307\/jsm_8_11_3236.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jsm\/article-pdf\/8\/11\/3236\/48476307\/jsm_8_11_3236.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,7]],"date-time":"2023-01-07T04:16:46Z","timestamp":1673065006000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jsm\/article\/8\/11\/3236\/6966870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11,1]]},"references-count":15,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2011,11,1]]},"published-print":{"date-parts":[[2011,11,1]]}},"URL":"https:\/\/doi.org\/10.1111\/j.1743-6109.2011.02415.x","relation":{},"ISSN":["1743-6109","1743-6095"],"issn-type":[{"value":"1743-6109","type":"electronic"},{"value":"1743-6095","type":"print"}],"subject":[],"published-other":{"date-parts":[[2011,11]]},"published":{"date-parts":[[2011,11,1]]}}}