{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T08:14:17Z","timestamp":1697444057561},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,8,28]],"date-time":"2011-08-28T00:00:00Z","timestamp":1314489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Asia-Pac J Clncl Oncology"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Carcinoids of the ampulla of Vater are infrequent tumors of which a quarter of cases have been detected in patients with type I neurofibromatosis. This hereditary disease is also associated with gastrointestinal stromal tumors (GIST). However, the coincidence of these three entities together have only been formerly detected in five cases. A 53 year\u2010old female patient, diagnosed with type I neurofibromatosis, with a malignant carcinoid of ampulla of Vater and multiple gastrointestinal stromal tumors in the duodenum and jejunum, was treated with total pancreatectomy and the excision of her intestinal tumors. Five\u2010years on, a follow\u2010up showed the patient to be well, and free from tumor recurrence. The coexistence of an ampullary carcinoid tumor, GIST and neurofibramatosis is very rare. Radical curative surgical resection is a good treatment option, but the optimal management of this is not yet well established.<\/jats:p>","DOI":"10.1111\/j.1743-7563.2011.01419.x","type":"journal-article","created":{"date-parts":[[2011,8,31]],"date-time":"2011-08-31T15:12:14Z","timestamp":1314803534000},"page":"193-196","source":"Crossref","is-referenced-by-count":0,"title":["Coincidence of GIST and pancreatic endocrine neoplasm in neurofibromatosis"],"prefix":"10.1111","volume":"7","author":[{"given":"Elias","family":"DOMINGUEZ\u2010COMESA\u00d1A","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"TOME\u2010ESPI\u00d1EIRO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose L","family":"ULLA\u2010ROCHA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"LORENZO\u2010LORENZO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel","family":"LEDE\u2010FERNANDEZ","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose L","family":"PORTELA\u2010SERRA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,8,28]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7443-z"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2005.03744.x"},{"key":"e_1_2_4_4_2","doi-asserted-by":"crossref","first-page":"7058","DOI":"10.3748\/wjg.v12.i43.7058","article-title":"Carcinoid of the ampulla of Vater: morphological features and clinical implications","volume":"12","author":"Poultsides GA","year":"2006","journal-title":"World J Gastroenterol"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/ejso.1999.0911"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s005350200159"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i19.2761"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-004-1438-2"},{"key":"e_1_2_4_9_2","first-page":"633","article-title":"Large somatostatin\u2010producing endocrine carcinoma of the ampulla of Vater in association with GIST in a patient with von Recklinghausen's disease. 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