{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:31:35Z","timestamp":1759048295068},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,3,12]],"date-time":"2012-03-12T00:00:00Z","timestamp":1331510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Immunogenetics"],"published-print":{"date-parts":[[2012,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>We report here a novel variant of HLA\u2010DRB1*10, DRB1*10:04, discovered in a Taiwanese volunteer bone marrow donor by a sequence\u2010based typing (SBT) method. The DNA sequence of DRB1*10:04 differs from DRB1*10:01:01, in exon 2, at nucleotide positions 296 (G\u2192A) and 303 (T\u2192G). The nucleotide changes caused an amino acid substitution at amino acid residue 70 (R\u2192Q). We hypothesize that the formation of DRB1*10:04 was probably the result of a gene recombination event where DRB1*10:01:01 received a minimum length of DNA sequence from DRB1*04:05:01, as the sequence of DRB1*10:04 is identical to DRB1*10:01:01 in exon 2 except the sequence from nucleotide 296 to nucleotide 303, which is identical to DRB1*04:05:01. The plausible HLA\u2010A, \u2010B, \u2010C and \u2010DRB1 haplotypes in association with DRB1*10:04 was deduced as A*01:01\u2010B*37:01\u2010C*06:02\u2010DRB1*10:04.<\/jats:p>","DOI":"10.1111\/j.1744-313x.2012.01106.x","type":"journal-article","created":{"date-parts":[[2012,3,12]],"date-time":"2012-03-12T07:31:34Z","timestamp":1331537494000},"page":"448-450","source":"Crossref","is-referenced-by-count":16,"title":["Discovery of the novel HLA\u2010DRB1*10:04 allele in a Taiwanese volunteer bone marrow donor and identification of the probable HLA\u2010A, \u2010B, \u2010C and \u2010DRB1 haplotype in association with DRB1*10:04"],"prefix":"10.1111","volume":"39","author":[{"given":"K. L.","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. K.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. H.","family":"Kao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. L.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Y.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,12]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1128"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2010.05.013"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2009.01226.x"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2005.00386.x"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2010.01466.x"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2005.10.017"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq998"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2006.00728.x"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-313X.2007.00704.x"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.2006.00529.x"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humimm.2009.01.015"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-313X.2010.00992.x"}],"container-title":["International Journal of Immunogenetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1744-313X.2012.01106.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1744-313X.2012.01106.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T17:52:01Z","timestamp":1698688321000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1744-313X.2012.01106.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,12]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["10.1111\/j.1744-313X.2012.01106.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1744-313x.2012.01106.x","archive":["Portico"],"relation":{},"ISSN":["1744-3121","1744-313X"],"issn-type":[{"value":"1744-3121","type":"print"},{"value":"1744-313X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,12]]}}}