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Non\u2010host resistance and quantitative resistance are broad spectrum forms of resistance, and all kinds of resistances are controlled by extremely diverse genes called \u201cR\u2010genes\u201d. R\u2010genes follow different mechanisms to defend plants and PAMP\u2010induced defenses in susceptible host plants are referred to as basal resistance. Genetic and phenotypic diversity are vital in maize (<jats:italic>Zea mays<\/jats:italic> L.); as such, genome wide association study (GWAS) along with certain other methodologies can explore the maximum means of genetic diversity. Exploring the complete genetic architecture to manipulate maize genetically reduces the losses from hazardous diseases. Genomic studies can reveal the interaction between different genes and their pathways. By confirming the specific role of these genes and protein\u2010protein interaction (proteomics) via advanced molecular and bioinformatics tools, we can shed a light on the most complicated and abstruse phenomena of resistance.<\/jats:bold><\/jats:p><jats:p><jats:disp-formula>\n<jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" position=\"anchor\" xlink:href=\"urn:x-wiley:16729072:media:JIPB1105:JIPB_1105_fu1\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic>\n<\/jats:disp-formula>\n\n[ <jats:bold>Jianbing Yan<\/jats:bold>\u2002(Corresponding author)]<\/jats:p>","DOI":"10.1111\/j.1744-7909.2012.01105.x","type":"journal-article","created":{"date-parts":[[2012,2,15]],"date-time":"2012-02-15T08:44:29Z","timestamp":1329295469000},"page":"134-151","source":"Crossref","is-referenced-by-count":60,"title":["Disease Resistance in Maize and the Role of Molecular Breeding in Defending Against Global Threat"],"prefix":"10.1111","volume":"54","author":[{"given":"Farhan","family":"Ali","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianbing","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,19]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2004.05.002"},{"key":"e_1_2_14_3_1","volume-title":"Plant Pathology.","author":"Agrios GN","year":"2005"},{"key":"e_1_2_14_4_1","first-page":"797","article-title":"Evaluation of antifungal efficacy of some plant extracts on Curvularia lunata, the causal organism of maize leaf spot","volume":"4","author":"Akinbode OA","year":"2010","journal-title":"Afr. 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