{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T08:21:42Z","timestamp":1778746902989,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:p><jats:bold>Abstract:\u2002<\/jats:bold> Reports analyzing the histopathological differences between encapsulating peritoneal sclerosis (EPS) and simple peritoneal sclerosis (non\u2010EPS) and those comparing the pathology of early and late EPS are limited. We present pathological comparisons between EPS and non\u2010EPS, also between the early and late EPS stages. We compared peritoneal membrane (PM) samples (Group B) of 12 EPS patients (Group A) and 23 non\u2010EPS cases regarding; mesothelial loss, submesothelial compact zone degenerated layer and compact zone thicknesses, densities of total and diseased vessels, fibrin stain, new membrane formation and degenerative changes. Group A was subdivided into 7 early (group A1) and 8 late (group A2) EPS cases; we compared both subgroups in the same manner and finally compared groups A1, A2, and B. No differences were found between groups A and B in the incidences of mesothelial detachment, new membrane formation and compact zone degenerative changes between the two groups. Furthermore, there were no differences in compact zone thickness, and vascular densities in the compact zone of respective vascular grade. Whereas, fibrin deposition and thickness of the submesothelial degenerated layer were significantly higher in group A than group B (<jats:italic>P<\/jats:italic>\u2003= 0.01 and 0.05, respectively), and the thickness of the compact zone was less in group A1 than in group A2 (<jats:italic>P<\/jats:italic>\u2003= 0.03). Positive fibrin stains and thick degenerative compact zone layers are important pathological findings in EPS. Angiogenesis, vasculopathy, new membrane formation, fibrosis and degenerative changes of the compact zone are not unique characteristics for EPS. Larger size studies are recommended to verify this issue.<\/jats:p>","DOI":"10.1111\/j.1744-9987.2007.00538.x","type":"journal-article","created":{"date-parts":[[2008,2,2]],"date-time":"2008-02-02T04:34:52Z","timestamp":1201926892000},"page":"33-41","source":"Crossref","is-referenced-by-count":33,"title":["Comparison Between the Pathology of Encapsulating Sclerosis and Simple Sclerosis of the Peritoneal Membrane in Chronic Peritoneal Dialysis"],"prefix":"10.1111","volume":"12","author":[{"given":"Ali M","family":"Sherif","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiraku","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Maruyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyasu","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keitaro","family":"Yokoyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuo","family":"Hosoya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makio","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,2]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"169","article-title":"Histologic criteria for diagnosing encapsulating peritoneal sclerosis in continuous ambulatory peritoneal dialysis patients","volume":"19","author":"Honda K","year":"2003","journal-title":"Adv Perit Dial"},{"key":"e_1_2_6_3_2","first-page":"200","article-title":"Treatment options for encapsulating peritoneal sclerosis based on progressive stage","volume":"17","author":"Kawanishi H","year":"2001","journal-title":"Adv Perit Dial"},{"key":"e_1_2_6_4_2","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1177\/089686080502504S10","article-title":"The plasma leak\u2010to\u2010response hypothesis: a working hypothesis on the pathogenesis of encapsulating peritoneal sclerosis after long\u2010term peritoneal dialysis treatment","volume":"25","author":"Nakayama M","year":"2005","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1177\/089686080502504S07","article-title":"The role of peritoneal fibrosis in encapsulating peritoneal sclerosis","volume":"25","author":"Miyazaki M","year":"2005","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_6_2","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1177\/089686080502504S05","article-title":"Encapsulating peritoneal sclerosis \u2013 a clinician's approach to diagnosis and medical treatment","volume":"25","author":"Nakamoto H","year":"2005","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfl054"},{"key":"e_1_2_6_8_2","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1177\/089686080302300204","article-title":"Association between an increased surface area of peritoneal micro vessels and a high peritoneal solute transport rate","volume":"23","author":"Numata M","year":"2003","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.6.1541"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-005-0349-8"},{"key":"e_1_2_6_11_2","first-page":"S30","article-title":"Morphological aspects of peritoneal sclerosis","volume":"14","author":"Garosi G","year":"2001","journal-title":"J Nephrol Dec"},{"key":"e_1_2_6_12_2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1681\/ASN.V132470","article-title":"Peritoneal Biopsy Study Group. Morphologic changes in the peritoneal membrane of patients with renal disease","volume":"13","author":"Williams JD","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_13_2","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1177\/089686080502504S08","article-title":"Experimental animal models of encapsulating peritoneal sclerosis","volume":"25","author":"Hoff CM","year":"2005","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"S349","DOI":"10.1177\/089686080102103S64","article-title":"New animal models for encapsulating peritoneal sclerosis, role of acidic solution","volume":"21","author":"Nakamoto H","year":"2001","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0940-2993(11)80261-7"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/089686080002004S04"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/089686080502504S04"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V133721"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(96)90501-6"},{"key":"e_1_2_6_20_2","first-page":"119","article-title":"Encapsulating peritoneal sclerosis in patients undergoing continuous ambulatory peritoneal dialysis in Japan","volume":"18","author":"Nakamoto H","year":"2002","journal-title":"Adv Perit Dial"},{"key":"e_1_2_6_21_2","first-page":"139","article-title":"Surgical treatment for encapsulating peritoneal sclerosis","volume":"18","author":"Kawanishi H","year":"2002","journal-title":"Adv Perit Dial"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1177\/039139888600900606"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(12)80677-9"},{"key":"e_1_2_6_24_2","first-page":"485","article-title":"Sclerosing encapsulating peritonitis secondary to CAPD: the effect of fibrotic debridement on further dialysis","volume":"47","author":"Klimopoulos S","year":"2002","journal-title":"J R Coll Surg Edinb"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.147.5.937"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1033050"},{"key":"e_1_2_6_27_2","first-page":"419","article-title":"Encapsulating peritoneal sclerosis a serious complication of peritoneal dialysis with uncharacteristic symptoms","volume":"59","author":"Kowalewska J","year":"2006","journal-title":"Wiad Lek"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fj.1744-9987.2007.00538.x","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/j.1744-9987.2007.00538.x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T17:52:49Z","timestamp":1697305969000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/j.1744-9987.2007.00538.x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["10.1111\/j.1744-9987.2007.00538.x"],"URL":"https:\/\/doi.org\/10.1111\/j.1744-9987.2007.00538.x","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2]]}}}